Protein Alignment Usp2 and F07A11.4

DIOPT Version :9

• Sequence 1: NP_001285528.1
• Gene: Usp2 / 33132
• FlyBaseID: FBgn0031187
• Length: 950
• Species: Drosophila melanogaster
• Sequence 2: NP_001364591.1
• Gene: F07A11.4 / 174780
• WormBaseID: WBGene00008547
• Length: 1135
• Species: Caenorhabditis elegans
• Alignment Length: 1269
• Identity: 232/1269 - (18%)
• Similarity: 364/1269 - (28%)
• Gaps: 592/1269 - (46%)

  Fly   100 RRSRAGEDSRNNNYNTSRAPTLINMR-RPSLFNGNQQPTTTNSTTINNTTSRNTTSNTSNGVLKY 163
            |.|.:....|::||:.|..|:....: .||.:      |...|..:|.|::.:|||:|.......
 Worm    12 RLSSSCSSIRSSNYSRSYTPSFNTFKYSPSSY------TPNISRNLNTTSTGSTTSDTPKLSSSS 70

  Fly   164 SVRSTTATATSTSTRNYGKLKPLNNNQTTAGVAMMNGHTNNNNNNTRNSSNINNGGNNNMQRQQQ 228
            :.||..:..|.:||                                  |:|:
 Worm    71 APRSRLSFTTPSST----------------------------------STNL------------- 88

  Fly   229 QHDDISFIDSDDPPATGGPEAGISTTKTSICYFKPITPPLQLRHEQNQVQQQEEQPQPSSSKSAS 293
                              |...|::.||  .|..|....:.:                |::.|.|
 Worm    89 ------------------PRTSITSHKT--LYSSPAAARVSV----------------STNDSLS 117

  Fly   294 HRYPRPKSTIIASAHSNFAASFEKFSGGLYRQTNGETNIESKTSSNARRYGIDSLSIKASIEKFN 358
            |..|          |:.            ||..:..:.||..|.::.:.|   ..|..:|:....
 Worm   118 HSTP----------HNT------------YRGISKYSTIERSTVADTKPY---YSSATSSLSSTY 157

  Fly   359 NLSGQKRQNPGSGSGI-------GPGSAT-----ASGLGGGRLSVASRSNHGSQAGGSSSNLQQR 411
            :.....|.:..|.|.:       ||.:.|     .|.      .:.|||::|  ...:.|...|:
 Worm   158 DSRRHSRSDRISSSTLPDVKIETGPTTRTHMVHPTSS------HIRSRSSYG--RSNTVSMFAQQ 214

  Fly   412 YSSDLDNIRVAAGYSSSLTRAAYRTT---------ATMNSVSTPVAVTSELGGPISGDGGETATA 467
            .....|.......|...:.:...|.|         .|.:|.|...:..||....::.....|:|.
 Worm   215 ARERADREEKDRDYKEWMQKEKDRETELGLETLYPTTSSSSSAQSSAQSEFRRSVAPSPTSTSTT 279

  Fly   468 ---MGQPTSKVTVRGAHSNRQPIECDSVVLTNKASKDATTAATPTVATATATHTPATSSVSTVTV 529
               .....|..|..|..|:..|:  |.::.|:.:|    .||||         .||.|.:||.|
 Worm   280 TPYRSNRYSSATRGGNSSSAAPL--DDIMSTSYSS----VAATP---------PPAYSQLSTST- 328

  Fly   530 TAAAPNSASDSVSRSLARSPISSTLARS----------GTGSSSTA---RSVL-----PPMTPTS 576
                                  |||.|:          |..|||..   :|::     ||..|.|
 Worm   329 ----------------------STLLRTRRERLEREEEGRNSSSMTPQPQSLVPPPPPPPPPPPS 371

  Fly   577 SRYWDRDSGTSRSSIGTSSALNSSSLKHNSDDGYKTASS--SRDEKSEGLC-------GLRNIGN 632
            :....|.....||   .|:|:.||:   :|...||..:.  ..:|..|.:|       |||||||
 Worm   372 AASNGRSGYLPRS---VSAAVISSA---SSSSVYKPTAMVLPYEEDREKVCVVEQGYTGLRNIGN 430

  Fly   633 TCFMNSVIQCLSHTQELTR-FLRSHHGSRSLST----KDQQILHEFAKLIQEMWTANVHTVTPME 692
            |||||:|:|.|.:..||.. |||:|:......|    .:.::...||..:.:||:.:...:.|.:
 Worm   431 TCFMNAVLQMLVNNIELREYFLRNHYQPEINETNPLGSEGRLAKAFADFMHQMWSGHQKAIEPTQ 495

  Fly   693 LKRAFSTKHRMYSDYNQQDAQEFLRFFLDSLHSALNSGVKGETLNIDDNLSDNKKADL-----TW 752
            :|...:.|...::::.|.||.|||.|.||.||..:|. ||.:.|.  ..:..:.:.||     .|
 Worm   496 IKNIVAEKASQFANFAQHDAHEFLSFLLDGLHEDVNR-VKKKPLT--GTVESHGRHDLDVSNEAW 557

  Fly   753 EWYTRHENSLVRDLFVGQLKSTLKCTTCGNTSVTFDPFWDLSVPLP------------------- 798
            :.:....:|:..|||.|||||.::|..|...|:|||||..|.||.|
 Worm   558 KNHILRNDSIFVDLFHGQLKSHVQCPNCDRVSITFDPFVYLPVPFPKNKQSTDLIFWPLENQTKP 622

  Fly   799 ----------------------------------------------------------------- 798
                                                                             
 Worm   623 YKLTVSYSTEGTVADFLSVVSETVRVPTRNLRACEAICHKFDKIYSLDMKVSDIVSPDRLFVFQT 687

  Fly   799 --------------------------------SSSRCKLEAC----------------------- 808
                                            .:|:.||:||
 Worm   688 HDEMEFNEEIVILHVLQRELYRKNTKHACHECGNSKLKLKACEECYDAVYCSKECQVANWSTGGH 752

  Fly   809 ----------------------------------------------------------------- 808
                                                                             
 Worm   753 REECSKRKPSETVGHPLIVSLPRSQLTYQHLYRVLEAKSRHTVTLFQQPQYESEGSEGDSLQAPS 817

  Fly   809 ----------------------------------------------------------------- 808
                                                                             
 Worm   818 RSIKKRNGVGAPPTFLQPPGESSSSSSVSSTPRRRSVAAEPRTKNQKMFEIRKLSGQNDSFGSHS 882

  Fly   809 ----------------------------------------------------------------- 808
                                                                             
 Worm   883 ISDDEACQSLESGGYVSVNWINQRNGKPYITIENRKDIDVDVEKSRQMNSRNMNGYVKSNNSETN 947

  Fly   809 ------LDLFIREEVLDGDEMPTCAKCKTRRKCTKSFTIQRFPKYLVIHLKRF---------SET 858
                  ||||...|.|..:|...|:.||...:.||...:.|.|..|:|.||||         |..
 Worm   948 PHLTQMLDLFSETERLKPEESWYCSTCKENVEATKKLQLYRLPPVLIIQLKRFVYTAFTYQSSMA 1012

  Fly   859 RWSKLSNIVEFPTSDSELNMGSYGANSNSNVHYSLYAISN---HMGSTAGGHYVALCK------H 914
            |.||.:..||:|.  ..|:|..:.|.::.:.:.::|.::.   |.|::..|||:::.:      .
 Worm  1013 RRSKDTRSVEYPL--ESLDMSPFLAETSPHPNSTMYDLTGVVCHSGNSYFGHYISMGRLADFDSS 1075

  Fly   915 PVSRKWHEFNDNIVSDALSENHLVSSSAYILFYE 948
            ....:|..|:|:.|: ..|.:.|.:..||:|||:
 Worm  1076 KTKIEWRNFDDSTVA-RQSTSTLQTEDAYLLFYK 1108

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp2	NP_001285528.1	UCH	624..947	CDD:278850	119/697 (17%)
		Peptidase_C19R	626..948	CDD:239139	119/689 (17%)
F07A11.4	NP_001364591.1	UBP12	<401..1110	CDD:227847	123/714 (17%)
		zf-MYND	716..756	CDD:396356	5/39 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1591
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940