DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wap and TTG1

DIOPT Version :9

Sequence 1:	NP_001245797.1	Gene:	wap / 33131	FlyBaseID:	FBgn0266848	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001318637.1	Gene:	TTG1 / 832523	AraportID:	AT5G24520	Length:	341	Species:	Arabidopsis thaliana

Alignment Length:	340	Identity:	181/340 - (53%)
Similarity:	234/340 - (68%)	Gaps:	26/340 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 YLAPWPLYSMNW-SVRPDKRFRLALGSFIEEYNNKVQIISLDED--TSEFSAKSTFDHPYPTTKI 75
            |.:|:|||:|.: |:|.....|:|:|||:|:|||::.|:|.|.|  |.:.....:|:||||.||:
plant    18 YDSPYPLYAMAFSSLRSSSGHRIAVGSFLEDYNNRIDILSFDSDSMTVKPLPNLSFEHPYPPTKL 82

  Fly    76 MWIPDS--KGVYPDLLATSGDYLRVWRAGEPDTRLE--CVLNNNKNSDFCAPLTSFDWNEVDPNL 136
            |:.|.|  :....||||:|||:||:|...|..:.:|  .||||:|.|:|||||||||||:|:|..
plant    83 MFSPPSLRRPSSGDLLASSGDFLRLWEINEDSSTVEPISVLNNSKTSEFCAPLTSFDWNDVEPKR 147

  Fly   137 VGTSSIDTTCTIWGLETGQPHARVYVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGADGSV 201
            :||.|||||||||.:|...          |:||||||||||:|||:..|    .:||||.|||||
plant   148 LGTCSIDTTCTIWDIEKSV----------VETQLIAHDKEVHDIAWGEA----RVFASVSADGSV 198

  Fly   202 RMFDLRHLEHSTIIYEDP-AHTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVARLSNH 265
            |:||||..||||||||.| ..|.||||||||||..|:||:.|||.:|:|||:|.|..|||.|..|
plant   199 RIFDLRDKEHSTIIYESPQPDTPLLRLAWNKQDLRYMATILMDSNKVVILDIRSPTMPVAELERH 263

  Fly   266 RACVNGIAWAPHSSCHICTAGDDHQALIWDIQQM--PRAIEDPILAYTAAEGEVNQIQWGATQPD 328
            :|.||.|||||.|..|||:.|||.|||||::..:  |..| ||:..|:|. .|:||:||.::|||
plant   264 QASVNAIAWAPQSCKHICSGGDDTQALIWELPTVAGPNGI-DPMSVYSAG-SEINQLQWSSSQPD 326

  Fly   329 WIAICYNKACEILRV 343
            ||.|.:....::|||
plant   327 WIGIAFANKMQLLRV 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wap	NP_001245797.1	WD40	19..295	CDD:421866	158/283 (56%)
		WD40 repeat	75..117	CDD:293791	19/45 (42%)
		WD40 repeat	125..171	CDD:293791	23/45 (51%)
		WD40 repeat	177..217	CDD:293791	25/39 (64%)
		WD40 repeat	224..264	CDD:293791	26/39 (67%)
		WD40 repeat	269..294	CDD:293791	17/24 (71%)
TTG1	NP_001318637.1	WD40	<82..293	CDD:421866	131/224 (58%)
		WD40 repeat	136..172	CDD:293791	23/45 (51%)
		WD40 repeat	178..214	CDD:293791	25/39 (64%)
		WD40 repeat	222..264	CDD:293791	26/41 (63%)
		WD40 repeat	267..292	CDD:293791	17/24 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0290
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	400	1.000	Inparanoid score	I466
OMA	1	1.010	-	-		QHG53629
OrthoDB	1	1.010	-	-		D750776at2759
OrthoFinder	1	1.000	-	-		FOG0003024
OrthoInspector	1	1.000	-	-		otm2535
orthoMCL	1	0.900	-	-		OOG6_102242
Panther	1	1.100	-	-	O	PTHR19919
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2014
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840