DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wap and Dcaf7

DIOPT Version :9

Sequence 1:	NP_001245797.1	Gene:	wap / 33131	FlyBaseID:	FBgn0266848	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_082222.1	Gene:	Dcaf7 / 71833	MGIID:	1919083	Length:	342	Species:	Mus musculus

Alignment Length:	342	Identity:	293/342 - (85%)
Similarity:	314/342 - (91%)	Gaps:	2/342 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 STAGKRKEIYKYLAPWPLYSMNWSVRPDKRFRLALGSFIEEYNNKVQIISLDEDTSEFSAKSTFD 67
            |..|||||||||.|||.:|:||||||||||||||||||:||||||||::.|||::|||..::|||
Mouse     2 SLHGKRKEIYKYEAPWTVYAMNWSVRPDKRFRLALGSFVEEYNNKVQLVGLDEESSEFICRNTFD 66

  Fly    68 HPYPTTKIMWIPDSKGVYPDLLATSGDYLRVWRAGEPDTRLECVLNNNKNSDFCAPLTSFDWNEV 132
            |||||||:|||||:|||||||||||||||||||.||.:|||||:|||||||||||||||||||||
Mouse    67 HPYPTTKLMWIPDTKGVYPDLLATSGDYLRVWRVGETETRLECLLNNNKNSDFCAPLTSFDWNEV 131

  Fly   133 DPNLVGTSSIDTTCTIWGLETGQPHARV-YVAGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVG 196
            ||.|:||||||||||||||||||...|| .|:|||||||||||||||||||||||||||||||||
Mouse   132 DPYLLGTSSIDTTCTIWGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVG 196

  Fly   197 ADGSVRMFDLRHLEHSTIIYEDPAHTALLRLAWNKQDPNYLATVAMDSCEVIILDVRVPCTPVAR 261
            |||||||||||||||||||||||.|..||||.|||||||||||:|||..||:|||||||||||||
Mouse   197 ADGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVAR 261

  Fly   262 LSNHRACVNGIAWAPHSSCHICTAGDDHQALIWDIQQMPRAIEDPILAYTAAEGEVNQIQWGATQ 326
            |:||||||||||||||||||||||.||||||||||||||||||||||||| ||||:|.:||.:||
Mouse   262 LNNHRACVNGIAWAPHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYT-AEGEINNVQWASTQ 325

  Fly   327 PDWIAICYNKACEILRV 343
            |||||||||...|||||
Mouse   326 PDWIAICYNNCLEILRV 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wap	NP_001245797.1	WD40	19..295	CDD:421866	239/276 (87%)
		WD40 repeat	75..117	CDD:293791	35/41 (85%)
		WD40 repeat	125..171	CDD:293791	38/46 (83%)
		WD40 repeat	177..217	CDD:293791	39/39 (100%)
		WD40 repeat	224..264	CDD:293791	34/39 (87%)
		WD40 repeat	269..294	CDD:293791	23/24 (96%)
Dcaf7	NP_082222.1	WD40	19..295	CDD:421866	239/275 (87%)
		WD 1	66..108		36/41 (88%)
		WD40 repeat	71..116	CDD:293791	38/44 (86%)
		WD 2	118..160		36/41 (88%)
		WD40 repeat	124..171	CDD:293791	38/46 (83%)
		WD 3	172..214		41/41 (100%)
		WD40 repeat	177..217	CDD:293791	39/39 (100%)
		WD40 repeat	224..264	CDD:293791	34/39 (87%)
		WD 4	264..304		38/39 (97%)
		WD40 repeat	269..294	CDD:293791	23/24 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845567
Domainoid	1	1.000	464	1.000	Domainoid score	I470
eggNOG	1	0.900	-	-		E1_KOG0290
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55930
Inparanoid	1	1.050	621	1.000	Inparanoid score	I875
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53629
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003024
OrthoInspector	1	1.000	-	-		oto95308
orthoMCL	1	0.900	-	-		OOG6_102242
Panther	1	1.100	-	-	LDO	PTHR19919
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1727
SonicParanoid	1	1.000	-	-		X2014
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790