DRSC/TRiP Functional Genomics Resources

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Protein Alignment tilB and Lrguk

DIOPT Version :9

Sequence 1:NP_608460.1 Gene:tilB / 33130 FlyBaseID:FBgn0014395 Length:395 Species:Drosophila melanogaster
Sequence 2:XP_006506776.1 Gene:Lrguk / 74354 MGIID:1921604 Length:1341 Species:Mus musculus


Alignment Length:330 Identity:69/330 - (20%)
Similarity:121/330 - (36%) Gaps:109/330 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 KKSEHNERLIS---------TLEEISLHQEDIEVIEHIQNWCRDL-------------------- 46
            ||.:.:..|||         ||.::.|...:||.|..::| |..|                    
Mouse   196 KKVDFSSNLISEMYDLSAYHTLTQLILDNNEIEEITGLEN-CISLTHLSLAGNKITTIKGLGTLP 259

  Fly    47 -KILLLQSNLIARLENLHKLKRLEYLNVAINNIERVENLEGCESLSKLDLTLNFIRELTSVESLC 110
             |:|.|.:|:|..:..|.:||.|:.|:::.|.|..::.||..:.|..::|..|.|:||:.:|.:.
Mouse   260 IKVLSLSNNMIETITGLEELKALQNLDLSHNQISSLQGLENHDLLEVINLEDNKIKELSEIEYIE 324

  Fly   111 GNYNLRELVLIGNPCVDYPHYRDYVVATLPQLNSLDCVEITPSERLRALRELSKNRSIIVQKQVE 175
            ....||.|.|:.||....|.|..:|:..|.:|..||..:|...|::.|:.:......::      
Mouse   325 NLPILRVLNLLRNPIQTKPEYWFFVIYMLLRLTELDQQKIKVEEKVFAVNKYDPPPEVV------ 383

  Fly   176 QDIERDEQRIRVAKQQSALAEHCAGIEDEEERIKAFWQAKSEHCPEI----------------RT 224
                             |:.:|...:.:...:.:..|.:.   .|.:                :.
Mouse   384 -----------------AVQDHMTHVVNSMSQPQRIWDST---LPSLDAPYPMLILTGPAACGKR 428

  Fly   225 EIARQHRLGRE---------RHETKSPLDPLKPQRNLFAPCGRPYNLNQAKLPFKFRDEADHYLL 280
            |:|  |||.|:         .|.|:.|.                         |...|..|::.:
Mouse   429 ELA--HRLCRQFSTYFRYGACHTTRPPY-------------------------FGEGDRVDYHFI 466

  Fly   281 QLEVY 285
            ..||:
Mouse   467 SQEVF 471

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tilBNP_608460.1 LRR_9 1..174 CDD:258718 51/192 (27%)
leucine-rich repeat 23..45 CDD:275378 7/21 (33%)
LRR_4 46..86 CDD:289563 14/60 (23%)
leucine-rich repeat 46..67 CDD:275378 8/41 (20%)
leucine-rich repeat 68..89 CDD:275378 6/20 (30%)
leucine-rich repeat 90..114 CDD:275378 7/23 (30%)
LrgukXP_006506776.1 leucine-rich repeat 131..150 CDD:275380
internalin_A <132..>333 CDD:380193 37/137 (27%)
leucine-rich repeat 151..172 CDD:275380
leucine-rich repeat 173..194 CDD:275380
leucine-rich repeat 195..216 CDD:275380 5/19 (26%)
leucine-rich repeat 217..238 CDD:275380 7/21 (33%)
leucine-rich repeat 258..281 CDD:275380 7/22 (32%)
leucine-rich repeat 282..300 CDD:275380 5/17 (29%)
leucine-rich repeat 304..328 CDD:275380 7/23 (30%)
GMPK 416..537 CDD:238026 14/83 (17%)
PHA03247 <678..1233 CDD:223021
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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