DRSC/TRiP Functional Genomics Resources

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Protein Alignment tilB and Lrriq3

DIOPT Version :9

Sequence 1:NP_608460.1 Gene:tilB / 33130 FlyBaseID:FBgn0014395 Length:395 Species:Drosophila melanogaster
Sequence 2:NP_001019478.1 Gene:Lrriq3 / 499732 RGDID:1591943 Length:633 Species:Rattus norvegicus


Alignment Length:447 Identity:90/447 - (20%)
Similarity:164/447 - (36%) Gaps:121/447 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 ITEELVRKK--SEHNERLISTLEEI------SLHQEDIEVIEHIQNWCRDLKILLLQSNLIARLE 60
            ||:||...:  |.:||.::...::.      .||   ::.:|::|: |..|::.:..:|.:..::
  Rat     6 ITKELTSHEEWSHYNENIVEDQKDFVFVKYNGLH---LKSMENLQS-CISLRVCIFSNNFVTDIQ 66

  Fly    61 NLHKLKRLEYLNVAINNIERVEN---LEGCESLSKLDLTLNFIRELTSVESLCGNYNLRELVLIG 122
            .|...|:|..|::..|.|:.:.:   ..|.::|..|.|..|...:|.::..|.|..||..|.:..
  Rat    67 PLQGCKKLIKLDLHGNQIKTLPDRTFWNGLKNLKLLYLHDNGFAKLKNICVLSGCVNLVGLTMFD 131

  Fly   123 NPCVDYPHYRDYVVATLPQLNSLDCVEITPSERLRALRELSKNRSIIVQKQVEQDIERDEQRIRV 187
            .|......||..:|.::..|.:||                   ..:|..:::.|:....| |.:.
  Rat   132 CPVSLKKGYRHVLVNSIWPLKALD-------------------HHVISDEEIIQNWHLPE-RFKT 176

  Fly   188 AKQQSALAEHCAG------IEDEEERIKAFWQAKSE----HCPE------IRTEIARQH---RLG 233
            . .||.....|..      .|||.:.||......:|    :.|.      ||..|.|:|   ...
  Rat   177 F-SQSLFFNICPAPIKGTTYEDEIKNIKHIISRINEILAHNSPVLIIQRWIRGFIVRKHLSPYFT 240

  Fly   234 RERH--------ETK-------------SPLDPLKPQRNLFAPCGRPYNLNQAKLPFKFRDEADH 277
            |:||        |||             ..:..:||:.|:.........:..:...||:..|...
  Rat   241 RKRHHDRMIRVLETKLICIGRNNEDKFLEDIFLIKPESNIKGKVAHWKQMRYSPDDFKYSTEYRK 305

  Fly   278 YL--LQLEVY-----------RH--------LDTSLIDVDVQTTYTRVTVK-------------- 307
            ::  |..|:.           ||        :.:...|.:|.|.:....:|              
  Rat   306 HISCLSYELKTKDIAGNSKQPRHHIQKGQNEMKSDSEDEEVDTKFRISAMKIPLCPSRSLKYRAM 370

  Fly   308 -KKIFQIAYSEEVKPDESTVQRSQITGHLVVNLKKLKVNELLIAKKSPTKSPAAPFD 363
             |:|....:.|.::|..:|.|:.|:         |.:.:|.|..:::...|..|..|
  Rat   371 LKEIKWDYFPEYLQPLPATRQKPQV---------KRETHEELKERRNFLASQRAGMD 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tilBNP_608460.1 LRR_9 1..174 CDD:258718 39/180 (22%)
leucine-rich repeat 23..45 CDD:275378 5/27 (19%)
LRR_4 46..86 CDD:289563 8/42 (19%)
leucine-rich repeat 46..67 CDD:275378 3/20 (15%)
leucine-rich repeat 68..89 CDD:275378 5/23 (22%)
leucine-rich repeat 90..114 CDD:275378 7/23 (30%)
Lrriq3NP_001019478.1 PPP1R42 36..>128 CDD:411060 23/95 (24%)
LRR 1 51..72 3/20 (15%)
leucine-rich repeat 52..73 CDD:275378 3/20 (15%)
LRR 2 73..94 4/20 (20%)
leucine-rich repeat 74..98 CDD:275378 5/23 (22%)
LRR 3 98..119 5/20 (25%)
leucine-rich repeat 99..115 CDD:275378 5/15 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 322..343 2/20 (10%)
DUF5401 <388..>586 CDD:375164 9/40 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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