DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tilB and sds22

DIOPT Version :9

Sequence 1:	NP_608460.1	Gene:	tilB / 33130	FlyBaseID:	FBgn0014395	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_650619.1	Gene:	sds22 / 42091	FlyBaseID:	FBgn0028992	Length:	326	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	51/158 - (32%)
Similarity:	76/158 - (48%)	Gaps:	24/158 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KKSEHNERLISTLEEISLHQEDIEVIEHIQNWCRDLKILLLQSNLIARLENLHKLKRLEYLNVAI 75
            ||.|:.|.|:: |.::.|.:..|..||::.... :|:||.||:|.|.::|||.||..|..|.|:.
  Fly   162 KKIENIEMLVN-LRQLFLGKNKIAKIENLDTLV-NLEILSLQANRIVKIENLEKLANLRELYVSE 224

  Fly    76 NNIERVENLEGCESLSKLDLTLNFIR------ELTSVESLCGNYN----------------LREL 118
            |.:|.:|||.....|..|||..|.::      :|..:|.|..|:|                |:.:
  Fly   225 NGVETIENLSENTKLETLDLAKNRLKGIANLEKLELLEELWLNHNGVDDWKDIELLKVNKALQTI 289

  Fly   119 VLIGNPCVDYPHYRDYVVATLPQLNSLD 146
            .|..||......||..:...||||..:|
  Fly   290 YLEYNPLAKDVRYRSKLRDILPQLQKID 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tilB	NP_608460.1	LRR_9	1..174	CDD:258718	51/158 (32%)
		leucine-rich repeat	23..45	CDD:275378	5/21 (24%)
		LRR_4	46..86	CDD:289563	20/39 (51%)
		leucine-rich repeat	46..67	CDD:275378	12/20 (60%)
		leucine-rich repeat	68..89	CDD:275378	8/20 (40%)
		leucine-rich repeat	90..114	CDD:275378	9/29 (31%)
sds22	NP_650619.1	leucine-rich repeat	43..62	CDD:275380
		LRR_8	61..117	CDD:290566
		leucine-rich repeat	63..84	CDD:275380
		LRR_4	83..125	CDD:289563
		leucine-rich repeat	85..106	CDD:275380
		LRR_8	105..183	CDD:290566	7/21 (33%)
		leucine-rich repeat	107..128	CDD:275380
		LRR_4	128..168	CDD:289563	3/5 (60%)
		leucine-rich repeat	129..150	CDD:275380
		LRR_4	149..189	CDD:289563	10/27 (37%)
		leucine-rich repeat	151..172	CDD:275380	5/9 (56%)
		leucine-rich repeat	173..194	CDD:275380	5/21 (24%)
		LRR_8	194..249	CDD:290566	25/54 (46%)
		LRR_4	194..235	CDD:289563	20/40 (50%)
		leucine-rich repeat	195..216	CDD:275380	12/20 (60%)
		leucine-rich repeat	217..238	CDD:275380	8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447143
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740