DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tilB and Lrrc23

DIOPT Version :9

Sequence 1:	NP_608460.1	Gene:	tilB / 33130	FlyBaseID:	FBgn0014395	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001381276.1	Gene:	Lrrc23 / 312707	RGDID:	1304779	Length:	345	Species:	Rattus norvegicus

Alignment Length:	167	Identity:	50/167 - (29%)
Similarity:	78/167 - (46%)	Gaps:	9/167 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ERLISTLEEISLHQEDIEVIEHIQNWCRDLKILLLQSNLIARLENLHKLKRLEYLNVAINNIERV 81
            ||| :.|..:.|....:|....|.  ...||.|.|..||:.::|.|..|..|..|::..|.||.:
  Rat   178 ERL-TNLHTLELRANQLETTIGIN--LPKLKNLYLAQNLLKKVEGLENLSNLTTLHLRDNQIETL 239

  Fly    82 ENL-EGCESLSKLDLTLNFIRELTSVESLCGNYNLRELVLIGNPCVDYPHYRDYVVATLPQLNSL 145
            :.. :..:||..|:|..|.|.:|..:..|.....||.|||:.|||.|...||...:..:..|..|
  Rat   240 DGFSKEMKSLQYLNLRSNMISDLGELAKLRDLPKLRALVLLDNPCADETDYRQEALVQMAHLERL 304

  Fly   146 DCVEITPSERLRALRELSKNRSIIVQKQVEQDIERDE 182
            |.......:|..|  |..:.|   ::::.||:::.|:
  Rat   305 DKEYYEDEDRAEA--EEIRQR---LKEEQEQELDPDQ 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tilB	NP_608460.1	LRR_9	1..174	CDD:258718	47/157 (30%)
		leucine-rich repeat	23..45	CDD:275378	4/21 (19%)
		LRR_4	46..86	CDD:289563	14/40 (35%)
		leucine-rich repeat	46..67	CDD:275378	9/20 (45%)
		leucine-rich repeat	68..89	CDD:275378	5/21 (24%)
		leucine-rich repeat	90..114	CDD:275378	7/23 (30%)
Lrrc23	NP_001381276.1	leucine-rich repeat	75..94	CDD:275380
		PPP1R42	80..306	CDD:411060	42/130 (32%)
		leucine-rich repeat	95..116	CDD:275380
		leucine-rich repeat	117..137	CDD:275380
		leucine-rich repeat	138..158	CDD:275380
		leucine-rich repeat	159..182	CDD:275380	3/4 (75%)
		leucine-rich repeat	183..203	CDD:275380	4/21 (19%)
		leucine-rich repeat	204..225	CDD:275380	9/20 (45%)
		leucine-rich repeat	226..248	CDD:275380	5/21 (24%)
		leucine-rich repeat	249..273	CDD:275380	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54194
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820