DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tilB and Lrrc46

DIOPT Version :9

Sequence 1:NP_608460.1 Gene:tilB / 33130 FlyBaseID:FBgn0014395 Length:395 Species:Drosophila melanogaster
Sequence 2:NP_001004201.1 Gene:Lrrc46 / 287653 RGDID:1303311 Length:323 Species:Rattus norvegicus


Alignment Length:220 Identity:71/220 - (32%)
Similarity:112/220 - (50%) Gaps:20/220 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 VLITEELVRKKS-------EHNERLISTLEEISLHQEDIEVIEHIQNW--CRDLKILLLQSNLIA 57
            |.|||.|:.|::       :.:|::..||:::...:.|.|.|..|.|.  .|::..|.||||.|.
  Rat    19 VHITEALITKRNLTFPEDEDLSEKMFHTLDDLETVRLDGEGITCIGNLERLRNIHSLYLQSNKIQ 83

  Fly    58 RLENLHKLKRLEYLNVAINNIERVENLEGCESLSKLDLTLNFIRELTSVESLCGNYNLRELVLIG 122
            |:|||..:..|.:|::|.|.|..||||...:.|..|||:.|.| |...::.|  ..:|..|.|.|
  Rat    84 RIENLACITSLRFLSLAGNQIRHVENLLDLQYLQFLDLSENLI-ETLKLDEL--PQSLLILNLCG 145

  Fly   123 NPCVDYPHYRDYVVATLPQLNSLDCVEI----TPSERLRALRELSK----NRSIIVQKQVEQDIE 179
            |||.:...||..|:..||.|..||...|    |..|..::..|..:    |.....::...:|:|
  Rat   146 NPCTNQDGYRKMVIGALPLLLDLDKQPILERWTSDEEDKSSDEEEEFPELNGPFCAERGFFKDLE 210

  Fly   180 RDEQRIRVAKQQSALAEHCAGIEDE 204
            ::..:.:..:||:||.||.:.:|.:
  Rat   211 QELHQHQERRQQAALTEHLSRMETQ 235

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tilBNP_608460.1 LRR_9 1..174 CDD:258718 62/188 (33%)
leucine-rich repeat 23..45 CDD:275378 6/23 (26%)
LRR_4 46..86 CDD:289563 19/39 (49%)
leucine-rich repeat 46..67 CDD:275378 10/20 (50%)
leucine-rich repeat 68..89 CDD:275378 9/20 (45%)
leucine-rich repeat 90..114 CDD:275378 8/23 (35%)
Lrrc46NP_001004201.1 LRR 1 49..70 5/20 (25%)
LRR_4 50..89 CDD:289563 15/38 (39%)
leucine-rich repeat 50..71 CDD:275378 5/20 (25%)
LRR_8 70..126 CDD:290566 25/55 (45%)
LRR_4 71..110 CDD:289563 17/38 (45%)
LRR 2 71..92 10/20 (50%)
leucine-rich repeat 72..93 CDD:275378 10/20 (50%)
LRR_4 92..130 CDD:289563 16/38 (42%)
LRR 3 93..114 9/20 (45%)
leucine-rich repeat 94..115 CDD:275378 9/20 (45%)
LRR 4 115..135 8/22 (36%)
leucine-rich repeat 116..137 CDD:275378 8/23 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 252..323
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0531
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.