Protein Alignment tilB and Drc3

DIOPT Version :10

• Sequence 1: NP_608460.1
• Gene: tilB / 33130
• FlyBaseID: FBgn0014395
• Length: 395
• Species: Drosophila melanogaster
• Sequence 2: NP_001013879.1
• Gene: Drc3 / 287371
• RGDID: 1309150
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 374
• Identity: 87/374 - (23%)
• Similarity: 158/374 - (42%)
• Gaps: 82/374 - (21%)

  Fly    30 QEDIEVIEHIQN-W-CRDLKILLLQSNLIARLENLHKLKRLEYLNVAINNIERVENLEGCESLSK 92
            |.|.:.|..|.| | ..:|:.|.|.:|:|.|:|.|..|..|.:|:::.||||.:|.|:...:|..
  Rat    49 QLDFQNILRIDNLWQFENLRKLQLNNNIIERIEGLENLTHLVWLDLSFNNIEAIEGLDTLVNLED 113

  Fly    93 LDLTLNFIRELTSVESL-------CGNYN---------------LRELVLIGNPCVDYPHYRDYV 135
            |.|:.|.|.::.|::.|       .||..               ||.|.|.|||..:...|:.::
  Rat   114 LSLSHNRISKIDSLDPLVNLQVLSLGNNQINNMMNIIYLRRFPCLRTLSLSGNPVSEAEEYKVFI 178

  Fly   136 VATLPQLNSLD-------CVEITPSERLRALRELSKNRSIIVQKQVEQDIERDEQRIRVAKQQSA 193
            .|.||.|..||       ..|:...:...::.|| |:|..::|.::|::..:.:   ::|:.:.|
  Rat   179 YAYLPDLVYLDFRRVDEQAREVAKMKHQYSIDEL-KHREALMQIRLEEEQAKQQ---KLAEHKMA 239

  Fly   194 LAEHCAG--------IEDEE-----------ERIKAFWQAKSEHCPEIRTEIARQHRLGRERHET 239
            ..||..|        .:|.|           |.::|:.......|..|       ...|..:.|.
  Rat   240 FVEHLNGPFLFDSMYSDDVEGNKLSYLPGVGELLEAYKDKFVIICLNI-------FEYGLSQQEK 297

  Fly   240 KSPLDPLKPQRNLFAPC---GRPYNLNQAKLPF-KFRDEADHYLLQLEVYRHLDTSLIDVDVQTT 300
            :      |.:.:.|..|   ....|.:|.||.. ||.::   :||.|...|. ::.|..::.:.|
  Rat   298 R------KIELDTFNECIQEAIQENQDQGKLKIAKFEEK---HLLNLNAIRE-ESDLFTMEQKLT 352

  Fly   301 YTRVTVKK-----KIFQIAYSEEVKPDESTVQR--SQITGHLVVNLKKL 342
            ....::.:     .|.::...|:::...:..:|  :.:.|..:.|::.|
  Rat   353 ECNESITELFNTLMILEMQLVEQLEETINVFERNITDLVGLFIENVQSL 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tilB	NP_608460.1	PPP1R42	<23..155	CDD:455733	47/155 (30%)
		leucine-rich repeat	23..45	CDD:275378	6/16 (38%)
		leucine-rich repeat	46..67	CDD:275378	9/20 (45%)
		leucine-rich repeat	68..89	CDD:275378	8/20 (40%)
		leucine-rich repeat	90..114	CDD:275378	9/30 (30%)
Drc3	NP_001013879.1	PPP1R42	42..>192	CDD:455733	46/142 (32%)
		LRR 1	44..65		6/15 (40%)
		leucine-rich repeat	48..66	CDD:275378	6/16 (38%)
		LRR 2	66..87		8/20 (40%)
		leucine-rich repeat	67..88	CDD:275378	9/20 (45%)
		LRR 3	88..109		8/20 (40%)
		leucine-rich repeat	89..110	CDD:275378	8/20 (40%)
		LRR 4	110..131		6/20 (30%)
		leucine-rich repeat	111..132	CDD:275378	7/20 (35%)
		LRR 5	132..153		2/20 (10%)
		leucine-rich repeat	158..169	CDD:275378	7/10 (70%)