DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tilB and Lrrc61

DIOPT Version :9

Sequence 1:	NP_608460.1	Gene:	tilB / 33130	FlyBaseID:	FBgn0014395	Length:	395	Species:	Drosophila melanogaster
Sequence 2:	NP_001103630.1	Gene:	Lrrc61 / 243371	MGIID:	2652848	Length:	259	Species:	Mus musculus

Alignment Length:	178	Identity:	49/178 - (27%)
Similarity:	74/178 - (41%)	Gaps:	21/178 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 CRDLKILLLQSNLIARLENLHKLKRLEYLNVAINNIERVENLEGCESLSKLDLTLNFIRELTSVE 107
            |.:|:.|.|..|.:..|..|..|::|..|||:.|.:..:|.|..||:|..|:...|.:.....::
Mouse    52 CLNLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLAACENLQSLNAAGNLLTTPGQLQ 116

  Fly   108 SLCG-----NYNLRE-LVLIGNPCVDYPHYRDYVVATLPQLNSLDCVEIT--PSERLRALRELSK 164
            .|.|     :..||: |..:.||......|...|...||.|..:|...::  .||..:..|:|..
Mouse   117 CLAGLQALEHLRLRDPLARLSNPLCANASYWAVVQELLPGLKVIDGERVSGRGSELYQLCRDLDS 181

  Fly   165 N---------RSIIVQKQVEQDIERDEQRIRVAKQQSALAEHCAGIED 203
            :         |:|..|..||... .:...||   ..|.|.|.|...:|
Mouse   182 SLRSGSSPGPRAIEAQPWVEPGY-WESWPIR---SSSILEEACRQFQD 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tilB	NP_608460.1	LRR_9	1..174	CDD:258718	40/147 (27%)
		leucine-rich repeat	23..45	CDD:275378	1/1 (100%)
		LRR_4	46..86	CDD:289563	14/39 (36%)
		leucine-rich repeat	46..67	CDD:275378	7/20 (35%)
		leucine-rich repeat	68..89	CDD:275378	8/20 (40%)
		leucine-rich repeat	90..114	CDD:275378	5/28 (18%)
Lrrc61	NP_001103630.1	internalin_A	<43..>138	CDD:380193	25/85 (29%)
		LRR 1	54..75		6/20 (30%)
		leucine-rich repeat	55..76	CDD:275380	7/20 (35%)
		LRR 2	76..97		7/20 (35%)
		leucine-rich repeat	77..98	CDD:275380	8/20 (40%)
		LRR 3	98..119		3/20 (15%)
		leucine-rich repeat	99..123	CDD:275380	5/23 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0531
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810