Protein Alignment HSPA9 and Hspa9

DIOPT Version :10

• Sequence 1: NP_004125.3
• Gene: HSPA9 / 3313
• HGNCID: 5244
• Length: 679
• Species: Homo sapiens
• Sequence 2: NP_001094128.2
• Gene: Hspa9 / 291671
• RGDID: 1311806
• Length: 679
• Species: Rattus norvegicus
• Alignment Length: 679
• Identity: 668/679 - (98%)
• Similarity: 670/679 - (98%)
• Gaps: 0/679 - (0%)

Human     1 MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDLGTTNS 65
            ||||||||||||||..|||.|.||||||.||||||||||.|||||||||||||||||||||||||
  Rat     1 MISASRAAAARLVGTTASRSPAAARHQDGWNGLSHEAFRFVSRRDYASEAIKGAVVGIDLGTTNS 65

Human    66 CVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDD 130
            |||||||||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||
  Rat    66 CVAVMEGKQAKVLENAEGARTTPSVVAFTPDGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDD 130

Human   131 PEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPA 195
            ||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 PEVQKDTKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPA 195

Human   196 YFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 YFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKG 260

Human   261 VFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQT 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 VFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQT 325

Human   326 DINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMT 390
            ||||||||||:|||||||||||||||||||||||:||||||||||||||||||||||||||||||
  Rat   326 DINLPYLTMDASGPKHLNMKLTRAQFEGIVTDLIKRTIAPCQKAMQDAEVSKSDIGEVILVGGMT 390

Human   391 RMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFT 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 RMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFT 455

Human   456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEV 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEV 520

Human   521 TFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMA 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   521 TFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMA 585

Human   586 EGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEM 650
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   586 EGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEM 650

Human   651 AYKKMASEREGSGSSGTGEQKEDQKEEKQ 679
            |||||||||||||||.|||||||||||||
  Rat   651 AYKKMASEREGSGSSSTGEQKEDQKEEKQ 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSPA9	NP_004125.3	Interaction with NFS1. /evidence=ECO:0000269|PubMed:26702583	1..432		420/430 (98%)
		dnaK	52..673	CDD:234715	615/620 (99%)
		Nucleotide-binding domain (NBD). /evidence=ECO:0000303|PubMed:24687350	63..431		363/367 (99%)
		Interaction with FXN and ISCU. /evidence=ECO:0000269|PubMed:26702583	432..679		245/246 (100%)
		Interdomain linker. /evidence=ECO:0000303|PubMed:24687350	432..441		8/8 (100%)
		Substrate-binding domain (SBD). /evidence=ECO:0000303|PubMed:24687350	442..679		235/236 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	656..679		21/22 (95%)
Hspa9	NP_001094128.2	Interaction with NFS1. /evidence=ECO:0000250|UniProtKB:P38646	1..432		420/430 (98%)
		dnaK	52..656	CDD:234715	599/603 (99%)
		Nucleotide-binding domain (NBD). /evidence=ECO:0000250|UniProtKB:P38646	63..431		363/367 (99%)
		Interaction with FXN and ISCU. /evidence=ECO:0000250|UniProtKB:P38646	432..679		245/246 (100%)
		Interdomain linker. /evidence=ECO:0000250|UniProtKB:P38646	432..441		8/8 (100%)
		Substrate-binding domain (SBD). /evidence=ECO:0000250|UniProtKB:P38646	442..679		235/236 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	655..679		22/23 (96%)