DRSC/TRiP Functional Genomics Resources

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Protein Alignment HSPA9 and Hspa9

DIOPT Version :10

Sequence 1:NP_004125.3 Gene:HSPA9 / 3313 HGNCID:5244 Length:679 Species:Homo sapiens
Sequence 2:NP_034611.2 Gene:Hspa9 / 15526 MGIID:96245 Length:679 Species:Mus musculus


Alignment Length:679 Identity:668/679 - (98%)
Similarity:670/679 - (98%) Gaps:0/679 - (0%)


- Green bases have known domain annotations that are detailed below.


Human     1 MISASRAAAARLVGAAASRGPTAARHQDSWNGLSHEAFRLVSRRDYASEAIKGAVVGIDLGTTNS 65
            ||||||||||||||.||||.|.|||.||.||||||||||.|||||||||||||||||||||||||
Mouse     1 MISASRAAAARLVGTAASRSPAAARPQDGWNGLSHEAFRFVSRRDYASEAIKGAVVGIDLGTTNS 65

Human    66 CVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDD 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 CVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNPNNTFYATKRLIGRRYDD 130

Human   131 PEVQKDIKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPA 195
            ||||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 PEVQKDTKNVPFKIVRASNGDAWVEAHGKLYSPSQIGAFVLMKMKETAENYLGHTAKNAVITVPA 195

Human   196 YFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKG 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 YFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKSEDKVIAVYDLGGGTFDISILEIQKG 260

Human   261 VFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQT 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 VFEVKSTNGDTFLGGEDFDQALLRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQT 325

Human   326 DINLPYLTMDSSGPKHLNMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMT 390
            ||||||||||:|||||||||||||||||||||||:||||||||||||||||||||||||||||||
Mouse   326 DINLPYLTMDASGPKHLNMKLTRAQFEGIVTDLIKRTIAPCQKAMQDAEVSKSDIGEVILVGGMT 390

Human   391 RMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFT 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   391 RMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFT 455

Human   456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEV 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   456 KLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRGVPQIEV 520

Human   521 TFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMA 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   521 TFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNMA 585

Human   586 EGIIHDTETKMEEFKDQLPADECNKLKEEISKMRELLARKDSETGENIRQAASSLQQASLKLFEM 650
            ||||||||||||||||||||||||||||||||||.|||.||||||||||||||||||||||||||
Mouse   586 EGIIHDTETKMEEFKDQLPADECNKLKEEISKMRALLAGKDSETGENIRQAASSLQQASLKLFEM 650

Human   651 AYKKMASEREGSGSSGTGEQKEDQKEEKQ 679
            |||||||||||||||||||||||||||||
Mouse   651 AYKKMASEREGSGSSGTGEQKEDQKEEKQ 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HSPA9NP_004125.3 Interaction with NFS1. /evidence=ECO:0000269|PubMed:26702583 1..432 421/430 (98%)
dnaK 52..673 CDD:234715 615/620 (99%)
Nucleotide-binding domain (NBD). /evidence=ECO:0000303|PubMed:24687350 63..431 364/367 (99%)
Interaction with FXN and ISCU. /evidence=ECO:0000269|PubMed:26702583 432..679 244/246 (99%)
Interdomain linker. /evidence=ECO:0000303|PubMed:24687350 432..441 8/8 (100%)
Substrate-binding domain (SBD). /evidence=ECO:0000303|PubMed:24687350 442..679 234/236 (99%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 656..679 22/22 (100%)
Hspa9NP_034611.2 Interaction with NFS1. /evidence=ECO:0000250|UniProtKB:P38646 1..432 421/430 (98%)
dnaK 52..673 CDD:234715 615/620 (99%)
Nucleotide-binding domain (NBD). /evidence=ECO:0000250|UniProtKB:P38646 63..431 364/367 (99%)
Interaction with FXN and ISCU. /evidence=ECO:0000250|UniProtKB:P38646 432..679 244/246 (99%)
Interdomain linker. /evidence=ECO:0000250|UniProtKB:P38646 432..441 8/8 (100%)
Substrate-binding domain (SBD). /evidence=ECO:0000250|UniProtKB:P38646 442..679 234/236 (99%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 656..679 22/22 (100%)

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