DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14621 and APE2

DIOPT Version :9

Sequence 1:	NP_001285522.1	Gene:	CG14621 / 33128	FlyBaseID:	FBgn0031183	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001078720.1	Gene:	APE2 / 834652	AraportID:	AT5G46110	Length:	415	Species:	Arabidopsis thaliana

Alignment Length:	312	Identity:	96/312 - (30%)
Similarity:	167/312 - (53%)	Gaps:	43/312 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 WYVISSSNNVIGKMVLNEFPFPMTVTLVQL------CSITLYSGPFFNLWRIRKYQDIPR----- 74
            ||.::...|::.|.:.|.||:|..|:::.|      |.|:         |.:    .:|:
plant   115 WYFLNVIFNILNKKIYNYFPYPYFVSVIHLFVGVVYCLIS---------WSV----GLPKRAPID 166

  Fly    75 PYYYRLIVPLALGKLLASVTSHISLWKVPVSYAHTVKATMPLFTVVLTRVFFGEKQPTLVYLSLL 139
            ....::::|:|:...|..|||::|...|.||:.||:||..|.|....::...|:..|..::|||.
plant   167 SNLLKVLIPVAVCHALGHVTSNVSFAAVAVSFTHTIKALEPFFNAAASQFIMGQSIPITLWLSLA 231

  Fly   140 PIITGVGIATVTEISFDMMGLISALISTMGFSMQNIFSKKVLKD---TNIHHLRLLHLLGKLSLF 201
            |::.||.:|::||:||:.:|.|||:||.:.|:.::|||||.:.|   ||::     ..:..::||
plant   232 PVVLGVAMASLTELSFNWLGFISAMISNISFTYRSIFSKKAMTDMDSTNVY-----AYISIIALF 291

  Fly   202 IFLPLWLYMDSFAVFRH---TAIKNLDY-RVIALLFADGVLNWLQNIIAFSVLSLVTPLTYAVAS 262
            :.:|..:.::...:..|   .||..:.. :.|:.||..|:...|.|.:|.:.|..|.|||:||.:
plant   292 VCIPPAIIVEGPKLLNHGFADAIAKVGMTKFISDLFWVGMFYHLYNQLATNTLERVAPLTHAVGN 356

  Fly   263 ASKRIFVIAVSLLILGNPVTWVNCVGMTLAIVGVLCYN-------RAKQLTR 307
            ..||:|||..|::|.||.::....:|..:||.||..|:       ..|::||
plant   357 VLKRVFVIGFSIVIFGNKISTQTGIGTGIAIAGVAMYSIIKAKIEEEKRVTR 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14621	NP_001285522.1	TPT	13..300	CDD:281186	92/296 (31%)
APE2	NP_001078720.1	tpt	106..404	CDD:129898	93/306 (30%)
APE2	NP_001078720.1	EamA	249..395	CDD:304911	50/150 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1307
eggNOG	1	0.900	-	-		E1_KOG1441
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1609
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1453018at2759
OrthoFinder	1	1.000	-	-		FOG0000579
OrthoInspector	1	1.000	-	-		otm2794
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11132
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930