DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14621 and Slc35e1

DIOPT Version :9

Sequence 1:	NP_001285522.1	Gene:	CG14621 / 33128	FlyBaseID:	FBgn0031183	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_001102577.2	Gene:	Slc35e1 / 498599	RGDID:	1561342	Length:	409	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	169/366 - (46%)
Similarity:	236/366 - (64%)	Gaps:	37/366 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GKRTGSRHIAVVLLMCLFWYVISSSNNVIGKMVLNEFPFPMTVTLVQLCSITLYSGPFFNLWRIR 67
            |.|.|:|    |..:||.||.:|:..||:.|::|:.||||:||:|..:.::.....|....||:.
  Rat    23 GAREGAR----VAALCLLWYALSAGGNVVNKVILSAFPFPVTVSLCHILALCAGLPPLLRAWRVP 83

  Fly    68 KYQDI------PRP---------YYYRLIVPLALGKLLASVTSHISLWKVPVSYAHTVKATMPLF 117
            ....:      |.|         :|.|.::|||.||..|||::|:|:||||||||||||||||::
  Rat    84 PAPPVSGPGPSPHPASGPLLPPRFYPRYVLPLAFGKYFASVSAHVSIWKVPVSYAHTVKATMPIW 148

  Fly   118 TVVLTRVFFGEKQPTLVYLSLLPIITGVGIATVTEISFDMMGLISALISTMGFSMQNIFSKKVLK 182
            .|:|:|:...|||.|.|||||:|||:||.:|||||:|||:.||:|||.:|:.||:|||||||||:
  Rat   149 VVLLSRIIMKEKQSTKVYLSLVPIISGVLLATVTELSFDVWGLVSALAATLCFSLQNIFSKKVLR 213

  Fly   183 DTNIHHLRLLHLLGKLSLFIFLPLWLYMD--SFAVFRHTAIKNLDYRVIALLFADGVLNWLQNII 245
            |:.|||||||::||..::|..:|.|:.:|  :|.|....|..:.....:.||...|..|:.||:|
  Rat   214 DSRIHHLRLLNILGCHAVFFMIPTWVLVDLSTFLVSSDLAYVSQWPWTLLLLVVSGFCNFAQNVI 278

  Fly   246 AFSVLSLVTPLTYAVASASKRIFVIAVSLLILGNPVTWVNCVGMTLAIVGVLCYNRAK----QLT 306
            |||:|:|::||:|:||:|:|||.||||||::|.||||..|.:||..||:||..||:.|    |..
  Rat   279 AFSILNLISPLSYSVANATKRIMVIAVSLIMLRNPVTSTNVLGMMTAILGVFLYNKTKYDANQQA 343

  Fly   307 RGREQP--TLPLSQTSYVKYSPLE---------QQADPYYR 336
            |....|  |..||...::: ||:|         ||.|..||
  Rat   344 RRHLLPVSTSDLSNREHLR-SPMEKPHNGALFPQQGDFQYR 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14621	NP_001285522.1	TPT	13..300	CDD:281186	148/303 (49%)
Slc35e1	NP_001102577.2	TPT	29..333	CDD:421389	149/307 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340549
Domainoid	1	1.000	293	1.000	Domainoid score	I1457
eggNOG	1	0.900	-	-		E1_KOG1441
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49075
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2612
OMA	1	1.010	-	-		QHG57710
OrthoDB	1	1.010	-	-		D1453018at2759
OrthoFinder	1	1.000	-	-		FOG0000579
OrthoInspector	1	1.000	-	-		oto96504
orthoMCL	1	0.900	-	-		OOG6_101650
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5824
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770