DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14621 and slc35e1

DIOPT Version :9

Sequence 1:	NP_001285522.1	Gene:	CG14621 / 33128	FlyBaseID:	FBgn0031183	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_998239.1	Gene:	slc35e1 / 406347	ZFINID:	ZDB-GENE-040426-2033	Length:	375	Species:	Danio rerio

Alignment Length:	323	Identity:	163/323 - (50%)
Similarity:	223/323 - (69%)	Gaps:	8/323 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RTGSRHIAVVLLMCLFWYVISSSNNVIGKMVLNEFPFPMTVTLVQLCSITLYSGPFFNLWRIRKY 69
            |.|.|    :.::||.||.:||..|||.|::||.||:|:||:|..:.||.::..|....|.:.:
Zfish    11 REGMR----IAVLCLCWYTVSSGGNVINKIILNSFPYPVTVSLFHIVSIIVFLPPLLRAWGVPR- 70

  Fly    70 QDIPRPYYYRLIVPLALGKLLASVTSHISLWKVPVSYAHTVKATMPLFTVVLTRVFFGEKQPTLV 134
            .::|..||...|:|||.||..|||::|.|:||||||||||||||||::.|:|:|:...|||.|.|
Zfish    71 TELPARYYRWYILPLAFGKYFASVSAHFSIWKVPVSYAHTVKATMPIWVVLLSRIIMKEKQTTKV 135

  Fly   135 YLSLLPIITGVGIATVTEISFDMMGLISALISTMGFSMQNIFSKKVLKDTNIHHLRLLHLLGKLS 199
            |:||:|||.||.:|||||:||||.||||||.:|:.||:|||||||||:||.||||.||::||..:
Zfish   136 YVSLIPIIGGVLLATVTELSFDMSGLISALAATLCFSLQNIFSKKVLRDTRIHHLHLLNILGFNA 200

  Fly   200 LFIFLPLWLYMD--SFAVFRHTAIKNLDYRVIALLFADGVLNWLQNIIAFSVLSLVTPLTYAVAS 262
            |...||.|:.:|  ||.:....:..:.....:.||...|..|:.||:||||||:||:||:||||:
Zfish   201 LLFMLPTWILVDLSSFLMDGDLSEVSSWTGTLMLLLISGFCNFAQNMIAFSVLNLVSPLSYAVAN 265

  Fly   263 ASKRIFVIAVSLLILGNPVTWVNCVGMTLAIVGVLCYNRAK-QLTRGREQPTLPLSQTSYVKY 324
            |:|||.||::|||:|.|||...|.:||..||:||..||:|| ...:..::..||:|....|.:
Zfish   266 ATKRIMVISISLLMLRNPVNTSNIIGMMTAILGVFLYNKAKYDSNQEAKKGLLPVSAQDVVSF 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14621	NP_001285522.1	TPT	13..300	CDD:281186	152/288 (53%)
slc35e1	NP_998239.1	TPT	14..303	CDD:281186	153/293 (52%)
		EamA	32..151	CDD:304911	62/119 (52%)
		EamA	158..303	CDD:279264	76/144 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580352
Domainoid	1	1.000	300	1.000	Domainoid score	I1400
eggNOG	1	0.900	-	-		E1_KOG1441
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H49075
Inparanoid	1	1.050	306	1.000	Inparanoid score	I2619
OMA	1	1.010	-	-		QHG57710
OrthoDB	1	1.010	-	-		D1453018at2759
OrthoFinder	1	1.000	-	-		FOG0000579
OrthoInspector	1	1.000	-	-		oto38760
orthoMCL	1	0.900	-	-		OOG6_101650
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1839
SonicParanoid	1	1.000	-	-		X5824
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800