DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14621 and Slc35e2

DIOPT Version :9

Sequence 1:	NP_001285522.1	Gene:	CG14621 / 33128	FlyBaseID:	FBgn0031183	Length:	373	Species:	Drosophila melanogaster
Sequence 2:	NP_796160.1	Gene:	Slc35e2 / 320541	MGIID:	2444240	Length:	405	Species:	Mus musculus

Alignment Length:	329	Identity:	95/329 - (28%)
Similarity:	165/329 - (50%)	Gaps:	35/329 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLMCLFWYVISSSNNVIGKMVLNEFP-FPMTVTLVQLCSITLYSGPFFNLWRIR------KYQDI 72
            |:....|:..|.....:.|.:|:... .|..:..||:.|.||       :..::      .||..
Mouse    76 LIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTL-------IGCVKIFVPCCLYQHK 133

  Fly    73 PR----PYYYRLIVPLALGKLLASVTSHISLWKVPVSYAHTVKATMPLFTVVLTRVFFGEKQPTL 133
            .|    |.:...::.:.|.:....|...:||..|.||:|.|||::.|:|||:::|:..||....|
Mouse   134 TRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLL 198

  Fly   134 VYLSLLPIITGVGIATVTEISFDMMGLISALISTMGFSMQNIFSKKVLKDTNIHHL--RLLHLLG 196
            |.|||:|::.|:.:.|.|||||:::|..:||.:.:...:||:||||:|........  .|.....
Mouse   199 VNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTS 263

  Fly   197 KLSLFIFLPLWLYMDSFAVFRHTAIKNLDYR--VIALLFADGVLNWLQNIIAFSVLSLVTPLTYA 259
            ..::.:.:|.|.:.....|...:. |:..|.  ::.||..||.|..||::.|::::..::|:|::
Mouse   264 AAAVALLIPAWTFFMDIPVIGRSG-KSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFS 327

  Fly   260 VASASKRIFVIAVSLLILGNPVTWVNCVGMTLAIVGVLCYNRAKQ------------LTRGREQP 312
            |||..|....|.:|:::.||.:|.::.:|..|..:|||.||:|:|            .:|..|..
Mouse   328 VASTVKHALSIWLSIIVFGNKITSLSAIGTILVTLGVLLYNKARQYQQETMQSLVTATSRNPEDD 392

  Fly   313 TLPL 316
            |.||
Mouse   393 TEPL 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14621	NP_001285522.1	TPT	13..300	CDD:281186	86/299 (29%)
Slc35e2	NP_796160.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
		TPT	73..368	CDD:331565	86/299 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	380..405		5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1441
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000579
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810