DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6t1 and CYP96A3

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_176713.1	Gene:	CYP96A3 / 842842	AraportID:	AT1G65340	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	555	Identity:	132/555 - (23%)
Similarity:	221/555 - (39%)	Gaps:	134/555 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAPFVGNVWNLLRGACCFGD 75
            |:.:|.|.:...       .|..|.:...:||    ::...|.:...|.:|.:..||.......|
plant     2 AIVIGLLEIFTA-------FVFFIFFQCLLLH----KKTPKPLLTNWPALGMLPGLLLQVPRIYD 55

  Fly    76 QFRELYESKEAA----GRAFVGIDVLHNHALLLRDPALIKRIMVEDFA------QFSSRFETTDP 130
            ...|:.|:.:..    |....|:|:     ||..||..|..|:..:||      :|...||....
plant    56 WITEVLEATDMTFCFKGPCLSGMDI-----LLTVDPVNIHYILSSNFANYPKGMEFKKIFEVVGD 115

  Fly   131 TC---------DTMGSQNLFFSKYETWRETHKIFAPFFAAGKVRNM-YGL---LENIGQKLEEHM 182
            :.         |...|.:..||..:        |..|:.:..||.: .||   |||...|
plant   116 SIFNVDSGLWEDMRNSSHAIFSNQD--------FQMFWVSTSVRKLRQGLVPILENAADK----- 167

  Fly   183 EQKLSGRDSMELEVKQLCA--LFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHL 245
                    ::.::::.|..  ||.|.:|....:..:..|::.|:.||......|:|....|  |:
plant   168 --------NILVDLQDLFQRFLFDTSLILMTGYDPKCLSVEMPKVEFGDAVDGVSDGVFYR--HV 222

  Fly   246 FTMFFFPRLSHRVGTHLYSEEYERFMRKSM---DYVL-----SQRAESGE------NRHDLIDIF 296
            ..:|.: ||.:.:|..:     |:.:::.:   |.:|     ::|.|...      :|.:.||:.
plant   223 KPVFLW-RLQYLIGVGV-----EKRLKRGLAVFDQLLEKIITAKREEINSHGTHHPSRGEAIDVL 281

  Fly   297 --------LQLKRTEPAESIIHRPDFFAAQAAF-LLLAGFDTSSSTITFALYELAKNTTIQDRLR 352
                    .:.|..||::      |.|...... .|:|..||:||.:|:..:.::||....:::|
plant   282 TYYMTMDTTKYKYLEPSD------DRFIKDTILGFLIAARDTTSSALTWFFWLMSKNPEAINKIR 340

  Fly   353 TELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFK 417
            .|:...:.......|.     .||||...|.|.||||||.                |:|..||.|
plant   341 QEVNKKMPRFDPADLE-----KLVYLHGAVCETLRLYPPV----------------PFNHKSPAK 384

  Fly   418 ---LRAG------TPVYISVLGIHRDAQYW-PNPEVFDPERFSAEQ-RQQHHP-MTYLPFGAGPR 470
               |.:|      ..:.||:..:.|....| .:.|.|.|||:.::. |.:|.| ..:|.|.||||
plant   385 PDVLPSGHRVDEKWKIVISMYALGRMKSVWGDDAEDFRPERWISDSGRLKHEPSYKFLAFNAGPR 449

  Fly   471 GCIGTLLGQLEIKVGLLHILNHFRVEVCE--RTLP 503
            .|:|..|..|::|.....|:.::.::|.|  :|.|
plant   450 ACLGKKLTFLQMKTVAAEIIRNYDIKVVEGHKTEP 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	116/471 (25%)
CYP96A3	NP_176713.1	p450	22..502	CDD:386267	127/528 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010