DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6t1 and CYP86A4

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_171666.1	Gene:	CYP86A4 / 839347	AraportID:	AT1G01600	Length:	554	Species:	Arabidopsis thaliana

Alignment Length:	553	Identity:	137/553 - (24%)
Similarity:	221/553 - (39%)	Gaps:	96/553 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 LLVVTIV---WLWQILHFWHWRRLGVPFVPAAPFVGNVWNLLRGACCFGDQFRE-LYESKEAAGR 89
            :|:|.||   ||| ......|  |..|.|  .|.:|::..|:...    |:..| :.|:..|.|.
plant     7 MLLVAIVTGYWLW-FKRISRW--LKGPRV--WPLLGSLPGLIEQR----DRMHEWITENLRACGG 62

  Fly    90 AF----VGIDVLHNHALLLR---DPALIKRIMVEDFAQFSSRFET--TDPTC-----DTMGSQNL 140
            .:    ..:..|.....|:.   ||..::.::       .:||:.  ..||.     |.:| |.:
plant    63 TYQTCIFAVPFLAKKQGLVTVTCDPKNLEHML-------KTRFDNYPKGPTWQSVFHDLLG-QGI 119

  Fly   141 FFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSME-LEVKQLCALFT 204
            |.|..:||....|..|..|....:|...|...|.|.|| .......:.:|:.| ::::.|....|
plant   120 FNSDGDTWLFQRKTAALEFTTRTLRQAMGRWVNRGIKL-RFCPILATAQDNAEPVDLQDLILRLT 183

  Fly   205 TDIIASLAFGIEAHSL--------------QNPEAEFRRMCIEVNDPRPK---RLLHLFTMFFFP 252
            .|.|..||||.:..:.              :..||..:|..|      ||   :|.....:....
plant   184 FDNICGLAFGKDTRTCAPGLPENGFASAFDRATEASLQRFII------PKFMWKLKKWLGLGLEV 242

  Fly   253 RLSHRVGTHLYSEEYERFMRKSMDYVLSQRAESG-ENRH-DLIDIFLQLKRTEPAESIIHRPDFF 315
            .||..:|.   .:||...:..:....|..:.||| ..|| ||:..|: :|:||.     :...|.
plant   243 SLSRSLGE---IDEYLAAVINTRKQELMSQQESGTHQRHDDLLSRFM-MKKTES-----YSDTFL 298

  Fly   316 AAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAAL---------QSSQDRQLSCDT 371
            ...|...:|||.||||..:::..:.:..:.|::|::..|:.:.|         .|..:..|..|.
plant   299 QHVALNFILAGRDTSSVALSWFFWLITMHPTVEDKIVREICSVLIETRGTDDVASWTEEPLGFDE 363

  Fly   372 VTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQ 436
            :..||||:..:.|.|||||......:...:.   |:.|.....|    ||:.|..|:....|...
plant   364 IDRLVYLKAAISETLRLYPSVPEDSKHVEND---DVLPDGTFVP----AGSSVTYSIYAAGRMKS 421

  Fly   437 YWPNPEV-FDPERFSAE---QRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEV 497
            .|....: |:|||:.:.   :...|....::.|.||||.|:|..|..|::|.....:|...|:.|
plant   422 TWGEDCLEFNPERWISPIDGKFINHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTV 486

  Fly   498 CERTLPEMRFDPK-AFVLTAHNGTYLRFVKNSL 529
                :|..:.:.| :..|...||..:...|..|
plant   487 ----VPGHKVEQKMSLTLFMKNGLLVNLYKRDL 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	113/471 (24%)
CYP86A4	NP_171666.1	PLN03195	5..513	CDD:215627	135/549 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010