DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp6t1 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	122/540 - (22%)
Similarity:	220/540 - (40%)	Gaps:	89/540 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VGSLVLLPVVLRGGCLLVVTIVW-------LWQILHFWHWRRLGVPFVPAAPFVGNVWNLLR--- 68
            :.::.||.:||   .|.||:.:|       |..::....:::.|:.........||:..:.:
plant     4 ISTINLLTIVL---LLFVVSKIWKACWILLLRPLMLSKRFKKQGISGPKYKILYGNLSEIKKMKK 65

  Fly    69 --GAC--------CFGDQFRELYESKEAAGRAFV---GID---VLHNHALLLRDPALIKRIMVED 117
              ..|        .|...|.:.::.....|..|:   |..   .:.||       .|.|:::
plant    66 EADLCVLDPNSNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNH-------ELAKQVL--- 120

  Fly   118 FAQFSSRFETT-----DPTCDTMGSQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQK 177
                ||:|..|     .|....:..:.|.|.:.:.|....:|..|.|:..:::.|...:.:...:
plant   121 ----SSKFGFTIIPVKRPEVFILFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLR 181

  Fly   178 L-EEHMEQKLSGRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKR 241
            : ||..:|:.:|...:::|:.:.....|.||||:.|||       :..||...:|....: ..|.
plant   182 IFEEWRKQRRNGEVLIKIEISKEFHKLTADIIATTAFG-------SSYAEGIELCRSQTE-LEKY 238

  Fly   242 LLHLFTMFFFPRLSH-RVGTHLYSEEYERFMRKSMDYVLSQRAES-------GENRHDLIDIFLQ 298
            .:...|..|.|...: ...|:|...|..:.::.|:..::..|.:|       |:   ||:.:.|.
plant   239 YISSLTNVFIPGTQYLPTPTNLKLWELHKKVKNSIKRIIDSRLKSKCKTYGYGD---DLLGVMLT 300

  Fly   299 LKRTEPAESIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQ 363
            ..::...|..: |.|....:......||..|:|..:|:....|:.:...|::||.|:  ..:..:
plant   301 AAKSNEYERKM-RMDEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLREEV--FNECGK 362

  Fly   364 DRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDR--CCNSRTGYDLSPWNGGSPFKLRAGTPVYI 426
            |:....||.:.|..:..|:.|.||||.|...:.|  ..:.:.|:          .::..||.:.|
plant   363 DKIPDTDTFSKLKLMNMVLMESLRLYGPVIKISREATQDMKVGH----------LEIPKGTSIII 417

  Fly   427 SVLGIHRDAQYW-PNPEVFDPERF-SAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHI 489
            .:|.:|||...| .:.|.|:|.|| :...:...||...|||..|||.||......:|.|..|..|
plant   418 PLLKMHRDKAIWGEDAEQFNPLRFENGISQATIHPNALLPFSIGPRACIAKNFAMVEAKTVLTMI 482

  Fly   490 LNHFRVEVCERTLPEMRFDP 509
            |..|::.:.    ||.:..|
plant   483 LQQFQLSLS----PEYKHTP 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	106/443 (24%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	122/535 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000