DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6t1 and Cyp4f40

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_006524820.1	Gene:	Cyp4f40 / 631304	MGIID:	3645508	Length:	551	Species:	Mus musculus

Alignment Length:	401	Identity:	105/401 - (26%)
Similarity:	181/401 - (45%)	Gaps:	38/401 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 LFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCALFT 204
            |..|..:.|....::..|.|.. .:...|..:.|....:......:|:...|..|.:.:..:|.|
Mouse   163 LLVSAGDKWNRHRRMLTPAFHF-NILKPYVKIFNDSTNIMHAKWLRLASGGSTRLNMFENISLMT 226

  Fly   205 TDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKR----LLHLFTMF--------FFP--RLS 255
            .|.:....|...::..:.| :::....:|::....||    |:|:..::        |:.  ||.
Mouse   227 LDTLQKCVFSFNSNCQEKP-SQYIAAILELSTLAVKRNEQLLMHVDLLYRLTPDGMRFYKACRLV 290

  Fly   256 HRVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQLKRTEPAESIIHRPDFFAAQAA 320
            |.....:..|.....::...|.::..:|:|  ...|.||:.| |.:.|..:.:  ..:...|:|.
Mouse   291 HDFTDAVIQERRRTLLKHGGDDIIKAKAKS--KTLDFIDVLL-LTKDEDGKEL--SDEDIRAEAD 350

  Fly   321 FLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEV 385
            ..:..|.||::|.:::.||.||::...|:|.|.|::..|:....:::..|.:..|.:|...:.|.
Mouse   351 TFMFRGHDTTASGLSWILYNLARHPEHQERCRQEVQELLRDRDPKEIEWDDLAQLPFLTMCIKES 415

  Fly   386 LRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFS 450
            |||:||...:.|||..    |:|..:|..   :..|....|::.|.|.:...|.:|||:||.||.
Mouse   416 LRLHPPVTMVSRCCTQ----DISLPDGRI---IPKGVICIINIFGTHHNPTVWRDPEVYDPFRFD 473

  Fly   451 AEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERTLP---EMRFDPKAF 512
            .|..|...|::::||.||||.|||......|:||.|...|..||:      ||   |.|..|: .
Mouse   474 PENIQARSPLSFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRI------LPDDKEPRRKPE-L 531

  Fly   513 VLTAHNGTYLR 523
            :|.|..|.:||
Mouse   532 ILRAEGGLWLR 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	100/391 (26%)
Cyp4f40	XP_006524820.1	p450	79..542	CDD:365848	103/399 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010