Protein Alignment Cyp6t1 and Cyp4a30b

DIOPT Version :10

• Sequence 1: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: XP_006503285.1
• Gene: Cyp4a30b / 435802
• MGIID: 3717145
• Length: 510
• Species: Mus musculus
• Alignment Length: 583
• Identity: 146/583 - (25%)
• Similarity: 223/583 - (38%)
• Gaps: 133/583 - (22%)

  Fly     2 IAVFSLIAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAP---FVGNV 63
            :::|.|.......|...||.||...|.||::.....:.:...|..:.| ..|.||.|   ..||.
Mouse     1 MSIFELSHITNVFGIFGLLQVVSLLGLLLLLLKSAQYYLHRQWLIKSL-QQFPPAPPPQWLFGNT 64

  Fly    64 ---WNLLRGACCFGDQFRELYESKEAAGRAFVGIDVLHNHA-LLLRDPALIKRIMVEDFAQFSSR 124
               .:|.:...|. ::|...|.      |...|     ||| :::.||..:|.|:
Mouse    65 LKDQDLQQILLCV-EKFPSTYV------RWLWG-----NHARVVIYDPDYMKVIL---------- 107

  Fly   125 FETTDPTCDTMGSQNLFFSKY----------ETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLE 179
             ..:||......|   ||:.:          :.|.:..::..|.|....::...|::.:....:.
Mouse   108 -GRSDPKVVRSYS---FFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVML 168

  Fly   180 EHMEQKLSGRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIE-VNDPRPKRLL 243
            :..||.:.  ....||:.|..:|.|.:.:...||..:. |:|..:....:..|: |.|     |.
Mouse   169 DKWEQLVD--QDCPLEIYQDISLMTMETMMKCAFSYQG-SVQLEDCRNSKSYIKAVED-----LT 225

  Fly   244 HLFTMFFFPRLSHRVGTH----LYS----------------EEYERF--MRKSMDYVLSQRAE-- 284
            ||.      .|..|.|.|    :||                :..||.  |||:.   |...||
Mouse   226 HLI------YLRVRNGFHQNNTIYSLSSNGRSFYHACQIAHKHTERVIRMRKAQ---LQNEAELE 281

  Fly   285 --SGENRHDLIDIFLQLKRTEPAESIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTI 347
              ..:.|.|.:||.| ..:||..:|:... |..|....| :..|.:|::|.|::..|.||.:...
Mouse   282 KFRKKKRLDFLDILL-FAQTEDGKSLSDE-DVRAEMDTF-MFEGHNTTASGISWIFYALATHPEH 343

  Fly   348 QDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYP-----------PTAFLDRCCNS 401
            |.|.|.|:::.|  .....::.:.:..:.|....:.|.|||||           |..|.|.|
Mouse   344 QQRCREEVKSIL--GNGTSVTLNHLDQMPYTTMCIKEALRLYPPIPGASRELSSPVTFPDGC--- 403

  Fly   402 RTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFG 466
                           .|..|..|.:|..|:|.:.:..||.|||||.||:....:|.|  .:|||.
Mouse   404 ---------------SLPKGFLVTLSFYGLHHNPRLRPNAEVFDPSRFAPGAPRQTH--AFLPFS 451

  Fly   467 AGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERTLPEMRFDP---KAFVLTAHNGTYLRFVK 526
            ||.|.|||......|:||.:...|..|.:      ||:....|   ...||.:.||.||...|
Mouse   452 AGTRNCIGKQFTMNELKVAVALTLLRFEL------LPDPTRVPILVSKIVLKSKNGIYLHTKK 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	CYP6-like	88..521	CDD:410679	121/484 (25%)
Cyp4a30b	XP_006503285.1	CYP4B-like	70..505	CDD:410771	126/508 (25%)