DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6t1 and Cyp9c1

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_523850.1	Gene:	Cyp9c1 / 37941	FlyBaseID:	FBgn0015040	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	497	Identity:	134/497 - (26%)
Similarity:	234/497 - (47%)	Gaps:	22/497 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IVWLWQILHFWHWRRLGVPFVPAAPFVGNV-WNLLRGACCFGDQFRELY-ESKEAAGRAFVGIDV 96
            :::.|.:..|.::.:.||......|.:||: |::|.|...:.....:|: ..|:   ....|:..
  Fly    16 LLYKWSVYTFGYFSKRGVAHEKPIPLLGNIPWSVLMGKESYIKHSIDLHLRLKQ---HKVYGVFN 77

  Fly    97 LHNHALLLRDPALIKRIMVEDFAQFSS-RFETTDPTCDT-MGSQNLFFSKYETWRETHKIFAPFF 159
            |.:....|.||.||:::.:::|..|:: |...|:...|| :.|::|...:...|::......|.|
  Fly    78 LRDPLYYLSDPELIRQVGIKNFDTFTNHRKGITEGFNDTSVISKSLLSLRDRRWKQMRSTLTPTF 142

  Fly   160 AAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPE 224
            .:.|:|.|:.|:.....:..:.::::|....| |||:|.....:|.|:||:.||||:.:|.::|.
  Fly   143 TSLKIRQMFELIHFCNVEAVDFVQRQLDAGTS-ELELKDFFTRYTNDVIATAAFGIQVNSFKDPN 206

  Fly   225 AEFRRMCIEVNDPRPKRLLHLFTMFFFPRLSHRVGTHLYSEEYERFMRKSMDYVLSQRAESGENR 289
            .||..:...:::......|.:......|:|...:...:.......:.:|.:...:..|.|....|
  Fly   207 NEFFSIGQRISEFTFWGGLKVMLYILMPKLMKALRVPVMDMNNVDYFKKLVFGAMKYRKEQSIVR 271

  Fly   290 HDLIDIFLQLKRTEPAE------------SIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELA 342
            .|:|.:.::.:|...||            ......|...||......|||:|.::.::|..|||.
  Fly   272 PDMIHLLMEAQRQFKAEQEGSAESAAQQDKAEFNDDDLLAQCLLFFSAGFETVATCLSFTSYELM 336

  Fly   343 KNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDL 407
            .|..:|::|..|:.|..:...::.|..||:.|:.||..||.|.||.:||...:||.|.|  .:.|
  Fly   337 MNPEVQEKLLAEILAVKEQLGEKPLDYDTLMGMKYLNCVVSESLRKWPPAFIVDRMCGS--DFQL 399

  Fly   408 SPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGC 472
            ....|.....||....|:|:|..:|.|...:|.||.|.||||..|.:.:....||||||.|.|.|
  Fly   400 KDEEGEVVVNLREDDLVHINVGALHHDPDNFPEPEQFRPERFDEEHKHEIRQFTYLPFGVGQRSC 464

  Fly   473 IGTLLGQLEIKVGLLHILNHFRVEVCERTLPEMRFDPKAFVL 514
            ||..|..:|:|..:..::..:.::..:||..:|......|.|
  Fly   465 IGNRLALMEVKSLIFQLVLRYHLKPTDRTPADMMSSISGFRL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	122/438 (28%)
Cyp9c1	NP_523850.1	p450	37..514	CDD:299894	130/476 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461027
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900