DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6t1 and Cyp9f3

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_001350862.1	Gene:	Cyp9f3 / 3772405	FlyBaseID:	FBgn0038034	Length:	433	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	119/454 - (26%)
Similarity:	195/454 - (42%)	Gaps:	98/454 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LWQILH--------FWHW--------RRLGVPFVPAAPFVGNVWNLLRGACCFGDQFRELYESKE 85
            ||:.|.        |:.|        :..|:.:.....::||:..:........|...:|| :|.
  Fly     2 LWEFLALFAIATALFYRWASANNDFFKDRGIAYEKPVLYLGNMAGMFLRKRAMLDIVCDLY-TKG 65

  Fly    86 AAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQF---SSRFETT---DP-TCDTMGSQNLFFS 143
            .:|: |.||.......|::|||.|||:|.::||..|   .:.|:|:   || ....:.|.:||..
  Fly    66 GSGK-FFGIFAQRQPLLMVRDPDLIKQITIKDFDHFINHRNEFDTSSDDDPHDMSNLFSSSLFSM 129

  Fly   144 KYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCALFTTDII 208
            :...|::.....:|.|...|:|.|:.|:..:.::..:.::|..|.....||::|..|..||.|:|
  Fly   130 RDARWKDMRSTLSPAFTGSKMRQMFQLMNQVAKEAVDCLKQDDSRVQENELDMKDYCTRFTNDVI 194

  Fly   209 ASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHL-------FTMFFFPRLSHRVGTHLYSEE 266
            ||.|||::.:|.::.|..|.:|        .|:|...       |.:.|..:..:::      .:
  Fly   195 ASTAFGLQVNSFKDRENTFYQM--------GKKLTTFTFLQNMKFILLFALKSLNKI------LK 245

  Fly   267 YERFMRKSMDY-------VLSQRAESGENRHDLIDIFLQLK---RTEPAESIIHRP----DFFAA 317
            .|.|.|||..|       .:..|.|....|.|:|::.::.:   :||..::...|.    | ..|
  Fly   246 VEIFDRKSTQYFVRLVLDAMKYRQEHNIVRPDMINMLMEARGIIQTEKTKASAVREWSDRD-IVA 309

  Fly   318 QAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVV 382
            |......|||:||:..:.|..:||.:|..:|.||..|::...|..:.::|.        ||.|||
  Fly   310 QCFVFFFAGFETSAVLMCFTAHELMENQDVQQRLYEEVQQVDQDLEGKELK--------YLDQVV 366

  Fly   383 DEVLRLYPPTAFLDRCCNSR----------------------------TGYDLSPWNGGSPFKL 418
            .||||.:||....||.||..                            :|:.||| .||...||
  Fly   367 SEVLRKWPPAIAFDRECNKEAKAVIYYLLKDYRFAPAKKSCIPLELISSGFQLSP-KGGFWIKL 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	106/384 (28%)
Cyp9f3	NP_001350862.1	p450	36..>388	CDD:325183	105/376 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461030
Domainoid	1	1.000	88	1.000	Domainoid score	I2119
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I1773
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	7.000