Protein Alignment Cyp6t1 and Cyp3a44

DIOPT Version :9

• Sequence 1: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_796354.1
• Gene: Cyp3a44 / 337924
• MGIID: 2449818
• Length: 504
• Species: Mus musculus
• Alignment Length: 515
• Identity: 154/515 - (29%)
• Similarity: 251/515 - (48%)
• Gaps: 70/515 - (13%)

  Fly    10 AALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWH--WRRLGVPFVPAAPFVGNVWNLLRGACC 72
            :||::.:||||.::|          |.|::.....|  :::.|:|.....||:|.|.|...|...
Mouse     5 SALSLDTLVLLAIIL----------VLLYRYGTRTHGLFKKQGIPGPKPLPFLGTVLNYYTGIWK 59

  Fly    73 FGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVED-FAQFSSRFETTDPTCDTMG 136
            |.   .|.||........|.|...|    |::.||..||.::|:| .:.|::|.|     ...:|
Mouse    60 FD---MECYEKYGKTWGLFDGQTPL----LVITDPETIKNVLVKDCLSVFTNRRE-----FGPVG 112

  Fly   137 --SQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQL 199
              |:.:..||.|.|:....:.:|.|.:|:::.|:.::|..|..|.:::.|:  ....|.:.:|.:
Mouse   113 IMSKAISISKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQE--AEKGMPVAMKDV 175

  Fly   200 CALFTTDIIASLAFGIEAHSLQNPEAEF-----RRMCIEVNDPRPKRLLHLFTMFFFPRLS---H 256
            ...::.|:|.|.:||:...||.|||..|     :.:.::..||.      ||::..||.|:   .
Mouse   176 LGAYSMDVITSTSFGVNVDSLNNPEDPFVEEAKKFLRVDFFDPL------LFSVVLFPLLTPVYE 234

  Fly   257 RVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQL----------KRTEPAESIIHR 311
            .:...::..:...|.:|.:|.:...|.:|  |:...:| ||||          |.:..|.|.:.
Mouse   235 MLNICMFPNDSIEFFKKFVDRMQESRLDS--NQKHRVD-FLQLMMNSHNNSKDKDSHKAFSNME- 295

  Fly   312 PDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLV 376
               ...|:...:.||::|:|||::|.||.||.:..||.:|:.|:..||.:....  :||||..:.
Mouse   296 ---ITVQSIIFISAGYETTSSTLSFTLYCLATHPDIQKKLQAEIDKALPNKATP--TCDTVMEME 355

  Fly   377 YLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNP 441
            ||..|::|.|||||....|:|.|..    |:. .||   ..:..|:.|.|....:|.|.|:||:|
Mouse   356 YLDMVLNETLRLYPIVTRLERVCKK----DVE-LNG---VYIPKGSMVMIPSYALHHDPQHWPDP 412

  Fly   442 EVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERT 501
            |.|.|||||.|.:....|..|||||.|||.|||.....:.:|:.:..:|.:|..:.|:.|
Mouse   413 EEFQPERFSKENKGSIDPYVYLPFGIGPRNCIGMRFALMNMKLAVTKVLQNFSFQPCQET 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	132/432 (31%)
Cyp3a44	NP_796354.1	p450	39..494	CDD:278495	143/471 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820