DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6t1 and Cyp318a1

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	NP_727590.1	Gene:	Cyp318a1 / 32172	FlyBaseID:	FBgn0030369	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	569	Identity:	134/569 - (23%)
Similarity:	207/569 - (36%)	Gaps:	183/569 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GCLLVVTIVW----LWQILHFWH---WRRLGVPFVPAAPFVGNVWNLLRGACCFG---------- 74
            |.||.|.:.|    .|:::  |.   ||  ||...|.      :|.||    |..
  Fly    11 GALLAVLLAWQQRKCWRLI--WQLNGWR--GVIQQPV------LWLLL----CINLHPNSILEKV 61

  Fly    75 DQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSRFETTDPTC-DTMGSQ 138
            .|:|..::...|   ..||..||    |.:.|||.::.::             ..|.| |....|
  Fly    62 SQYRVHFQRPLA---VLVGTRVL----LYIDDPAGMECVL-------------NAPECLDKTFLQ 106

  Fly   139 NLFF-------SKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQK--LSGR----- 189
            :.||       ::.:.|:...|...|.|:...|.:.:.:..::|.::.|..:.:  |.|:
  Fly   107 DGFFVRRGLLHARGQKWKLRRKQLNPAFSHNIVASFFDVFNSVGNQMVEQFQTQTNLHGQAVKFT 171

  Fly   190 ---DSME---LEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPR-PKRLLHLFT 247
               |.:.   |||..|..:.|......|.....|||       ::|: :|::..| .|..|.:
  Fly   172 AAEDLLSRAVLEVSCLTIMGTPTNFTQLDDAHIAHS-------YKRL-LEISAVRVVKPWLQI-- 226

  Fly   248 MFFFPRLSHR-VGTHLYSEEYERFMRKSMDYV---------------------LSQRAESGENRH 290
                 ||.|| :...|| ||.::..:...|:|                     ..:.|.:|..|.
  Fly   227 -----RLLHRLLAPELY-EESKKCAKLLEDFVGGIVRTKHRNWRLRDAVGGEKSGEDASNGWQRR 285

  Fly   291 DLIDIFLQLKRT--EPAESIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNT-TIQDRLR 352
            ..|:...||...  ...|.|:.       :|..::|..|:|.|::|..||..||.|. ..|.||.
  Fly   286 IFIEQIFQLAANGEMTLEEIMD-------EAQSMVLVSFETVSNSIMLALLCLATNKGDCQRRLL 343

  Fly   353 TELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFK 417
            .|:||.:...  .|:..:.:..|.||...|.|.|||....                      |..
  Fly   344 AEIRALVPDV--GQVGLEQLQQLRYLDAFVSESLRLLATV----------------------PMN 384

  Fly   418 LR--------AG----------TPVYISVLGIHRDAQYW-PNPEVFDPERF-------------- 449
            ||        ||          :.|.:....:.||.::| .|...|||:||
  Fly   385 LRHVSRDFRLAGRQHETIVPQNSIVVLDTFNMQRDERWWGANARQFDPQRFLDQEEEQLSKGHND 449

  Fly   450 --SAEQRQQ---HHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHF 493
              |.|:|:|   .|..::|||..|.|.|||...|...:||.|:.::.:|
  Fly   450 SGSGEKRRQRDRRHSYSFLPFSNGLRSCIGRRYGLFIMKVFLVKLITNF 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	115/488 (24%)
Cyp318a1	NP_727590.1	p450	42..503	CDD:299894	123/534 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.010