Protein Alignment Cyp6t1 and Cyp3a23-3a1

DIOPT Version :9

• Sequence 1: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 513
• Identity: 146/513 - (28%)
• Similarity: 245/513 - (47%)
• Gaps: 64/513 - (12%)

  Fly     8 IAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWH--WRRLGVPFVPAAPFVGNVWNLLRGA 70
            :.:||.:.:.|||.|||          |.|:......|  :::.|:|.....||.|.|.|...|.
  Rat     3 LLSALTLETWVLLAVVL----------VLLYGFGTRTHGLFKKQGIPGPKPLPFFGTVLNYYMGL 57

  Fly    71 CCFGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVED-FAQFSSRFETTDPTCDT 134
            ..|..:..:.|      |:.: |:.........:.|..:||.::|:: |:.|::| ....|. ..
  Rat    58 WKFDVECHKKY------GKIW-GLFDGQMPLFAITDTEMIKNVLVKECFSVFTNR-RDFGPV-GI 113

  Fly   135 MGSQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQL 199
            || :.:..||.|.|:....:.:|.|.:|:::.|:.::|..|..|.:::.|: .|:   .:.||::
  Rat   114 MG-KAISVSKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQE-KGK---PVPVKEV 173

  Fly   200 CALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHL-------FTMFFFPRLS-- 255
            ...::.|:|.|.:||:...||.||:..|    :|    :.|:||.:       .::..||.|:
  Rat   174 FGAYSMDVITSTSFGVNVDSLNNPKDPF----VE----KAKKLLRIDFFDPLFLSVVLFPFLTPV 230

  Fly   256 -HRVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQL-----KRTEPAESIIHRPDF 314
             ..:...::.::...|.:|.:..:...|.:|.:...  :| ||||     ..::..||.....|.
  Rat   231 YEMLNICMFPKDSIEFFKKFVYRMKETRLDSVQKHR--VD-FLQLMMNAHNDSKDKESHTALSDM 292

  Fly   315 -FAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYL 378
             ..||:...:.||::.:|||::|.|:.||.:...|.:|:.|:..||.:....  :.|||..:.||
  Rat   293 EITAQSIIFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPP--TYDTVMEMEYL 355

  Fly   379 RQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEV 443
            ..|::|.|||||....|:|.|......     ||   ..:..|:.|.|....:|||.|:||.||.
  Rat   356 DMVLNETLRLYPIGNRLERVCKKDVEI-----NG---VFMPKGSVVMIPSYALHRDPQHWPEPEE 412

  Fly   444 FDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERT 501
            |.|||||.|.:....|..|||||.|||.|||.....:.:|:.|..:|.:|..:.|:.|
  Rat   413 FRPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKET 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	124/428 (29%)
Cyp3a23-3a1	NP_037237.2	p450	39..492	CDD:278495	134/467 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920