Protein Alignment Cyp6t1 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 123/516 - (23%)
• Similarity: 221/516 - (42%)
• Gaps: 105/516 - (20%)

  Fly    45 HWRRLGVPFVPAAPFVGNVWNLL--RGACCFGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDP 107
            ||            |:||:....  :....:.|..|...|..|..|..| ||.......:::.:.
 Worm    42 HW------------FLGNLKQTAERKEKLGYDDANRWFNELHEQYGETF-GIYYGSQMNIVISNE 93

  Fly   108 ALIKRIMVEDFAQFSSR-----FETTDPTCDTMGSQNLFFSKYET-WRETHKIFAPFFAAGKVRN 166
            ..||.:.:::|:.||.|     :|....|.      :|..:.|.: |:.|....||.|:.||::.
 Worm    94 KDIKEVFIKNFSNFSDRSVPSIYEANQLTA------SLLMNSYSSGWKHTRSAIAPIFSTGKMKA 152

  Fly   167 MYGLLENIGQKLE---EHMEQKLSGRDSMEL--EVKQLCALFTTDIIASLAFGIEAHSLQNPEAE 226
            |.   |.|..|::   :.:.:|.|.....::  :.:.|    |.|:|...||.|:::..::....
 Worm   153 MQ---ETINSKVDLFLDILREKASSGQKWDIYDDFQGL----TLDVIGKCAFAIDSNCQRDRNDV 210

  Fly   227 F---RRMCIEVNDPRPKRLLHLFTMFFFPRLSHRVGTHLY----------------SEEYERFMR 272
            |   .:..|...|.|..:::....:  .|.|| .....||                |..|||
 Worm   211 FYVNAKKYISNIDIRHSKIIAASVL--LPELS-TFWKALYKYTPLADAEIPLVEGLSNVYER--- 269

  Fly   273 KSMDYVLSQRAESGENRHDLIDIFLQLK--RTEP--AESIIHRPDFFAAQAAFLLLAGFDTSSST 333
                    :|...|.:..||:.:.|..:  :::|  .:.:|.  :.||     .||||::|:|:.
 Worm   270 --------RRGGEGSDSVDLLKLLLNREDDKSKPMTKQEVIE--NCFA-----FLLAGYETTSTA 319

  Fly   334 ITFALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTA-FLDR 397
            :|:..|.|:|...:|.:|..|:   :::.::..|:.|::..:.||..|..|.||.|||.. |:.|
 Worm   320 MTYCSYLLSKYPNVQQKLYEEI---MEAKENGGLTYDSIHNMKYLDCVYKETLRFYPPVIHFIRR 381

  Fly   398 CCNSRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTY 462
            .|..    |::......|    .|..|......:||:.:.|.:||.|.||||. ...::...:.:
 Worm   382 LCRE----DITIRGQFYP----KGAIVVCLPHTVHRNPENWDSPEEFHPERFE-NWEEKSSSLKW 437

  Fly   463 LPFGAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERTLPEMRFDPKAFVLTAHNGTYLR 523
            :|||.|||.|:|....::|.|..::.:|:.|.::         :|:.:|.::...||..:|
 Worm   438 IPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELK---------QFEGEADLIPDCNGVIMR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	CYP6-like	88..521	CDD:410679	113/467 (24%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	114/473 (24%)