DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6t1 and tbxas1

DIOPT Version :9

Sequence 1:	NP_608457.1	Gene:	Cyp6t1 / 33127	FlyBaseID:	FBgn0031182	Length:	529	Species:	Drosophila melanogaster
Sequence 2:	XP_031753608.1	Gene:	tbxas1 / 100327243	XenbaseID:	XB-GENE-994325	Length:	532	Species:	Xenopus tropicalis

Alignment Length:	551	Identity:	145/551 - (26%)
Similarity:	244/551 - (44%)	Gaps:	83/551 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GCLLVVTIV--------WLWQILHFWHWRRLGVPFVPAAPFVGNVWNLLRGACCFGDQFRELYES 83
            ||.:.:|:|        | :.:..||...:.|:......||:||:....:|   |.:..|.|.::
Frog    11 GCTVTLTLVAGFLGLLYW-YSVSAFWQLEKAGIKHPKPLPFIGNIMLFQKG---FWEGDRHLLKT 71

  Fly    84 KEAAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSRFETTDPTCDTMGSQNLFFSKYETW 148
            .......::|    ....:::.:|..||:::.:||..|::|.:..:.....| |.:|...:.:.|
Frog    72 YGPICGYYMG----RRPMIVIAEPDAIKQVLQKDFVNFTNRMQRLNLVTKPM-SDSLLCLRDDKW 131

  Fly   149 RETHKIFAPFFAAGKVRNMYGLLENIGQKLEEH-MEQKLSGRDSMELEVKQLCALFTTDIIASLA 212
            :....:..|.|:|.:::.|..|:......|.|: ||...||.   ...|::..|.||.|::||:|
Frog   132 KRVRSVLTPSFSAARMKEMCPLINQCCDVLVENLMEYASSGE---ACNVQRCYACFTMDVVASVA 193

  Fly   213 FGIEAHSLQNPEAEFRRMCIEVNDPRPKRLLHLFTMF--------FFPRLSHRVGTHLYSEEYER 269
            ||.:..|.::.:....:.|        ||.|.|||.|        .||.:...:...|.::..:|
Frog   194 FGTQVDSQRDSDHPLVQNC--------KRFLELFTPFKPVVLLCLAFPSIMIPIARRLPNKHRDR 250

  Fly   270 ----FMRKSMDYV-LSQRAESGENRHDLIDIFLQLKRTEPAESIIH------------------- 310
                |::...|.: ..:.....|.|.|.:.:.|..:.:....|:.|
Frog   251 INSFFLKVIRDIIAFRENQPPNERRRDFLQLMLDARDSAGHVSVDHFDIVNQADLSVPQNQDRGQ 315

  Fly   311 -----------RPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQD 364
                       ..:....||...|:||::|:.|.::||.|.||.:...|::|..|:...  |.:.
Frog   316 DPPRKSTQKTLNEEEILGQAFIFLIAGYETTCSLLSFASYLLATHPDCQEKLLKEVDEF--SQEH 378

  Fly   365 RQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVL 429
            .:...:||..|.|:..|::|.||:|||.....|    ....|.:....|.|    ||..|.|.:.
Frog   379 EEADYNTVHDLPYMEMVINETLRMYPPAYRFAR----EAARDCTVMGLGIP----AGAVVEIPIG 435

  Fly   430 GIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFR 494
            .:..|.::|..||.|:||||:||::|:.||..:||||||||.|||..|..||.|:.|..:|..||
Frog   436 CLQNDPRFWHEPEKFNPERFTAEEKQKRHPFLFLPFGAGPRSCIGMRLALLEAKITLYRVLRKFR 500

  Fly   495 VEVCERTLPEMRFDPKAFVLTAHNGTYLRFV 525
            .:.|:.|...::..... .|...:|.|:|.|
Frog   501 FQTCDLTQIPLQLSAMT-TLRPKDGVYVRVV 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	124/467 (27%)
tbxas1	XP_031753608.1	cytochrome_P450	71..526	CDD:425388	126/481 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3174
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060