Protein Alignment Cyp6t1 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 554
• Identity: 141/554 - (25%)
• Similarity: 229/554 - (41%)
• Gaps: 96/554 - (17%)

  Fly     8 IAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFWHWRRLGVPFVPAAPFVGNVWNLLRGACC 72
            ::..|.|.|::       |..||:|..|..:  || ..|....:...|:.||   .|       .
Mouse    15 LSGFLQVASVL-------GLLLLLVKAVQFY--LH-RKWLLKALQQFPSPPF---HW-------F 59

  Fly    73 FG-DQFRELYESKEAAGRA----------FVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSRFE 126
            || :||:...|.||.....          |.|    .|..|.:.||..:|.|:.....:.:..:.
Mouse    60 FGHEQFKGEQELKEVVSCIEHFPSAFPCWFWG----SNAYLTVYDPDYMKVILGRSDPKANGIYR 120

  Fly   127 TTDPTCDTMGSQNLFFSKYETWRETHKIFAPFF----AAGKVRNMYGLLENIGQKLEEHMEQKLS 187
            ...|..    ...|.....:.|.:..::..|.|    ....|:||...:..:..|.|     :|:
Mouse   121 LLAPWI----GYGLLLLNGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWE-----RLA 176

  Fly   188 GRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEFRRMCIEVND------PRPKRLLH-- 244
            |:|| .:|:.|..:|.|.|.:...||..:. |:| .:..::.....:.|      .|.:.:.|
Mouse   177 GQDS-SIEIFQHISLMTLDTVMKCAFSHKG-SVQ-VDGNYKTYLQAIGDLNNLFHSRVRNIFHQN 238

  Fly   245 --LFTMFFFPRLSHRVG--THLYSEEYERFMRKSMDYVLSQRAESGE-------NRHDLIDIFLQ 298
              ::.:....||:.:..  .|.:::...: |||      .|..:.||       .|.|.:||.|
Mouse   239 DTIYRLSSNGRLAKQACQLAHDHTDGVIK-MRK------DQLQDEGELENIKKKRRLDFLDILL- 295

  Fly   299 LKRTEPAESIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQ 363
            ..|.|..:|:..:.  ..|:....:..|.||::|.:::..|.||.:...|.|.|.|:::.|  ..
Mouse   296 FARMENGDSMSDKD--LRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLL--GD 356

  Fly   364 DRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISV 428
            ...::.|.:..:.|....:.|.||||||...:.|..::...:.    :|.|   |..|..|.:|:
Mouse   357 GSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFP----DGRS---LPKGVQVTLSI 414

  Fly   429 LGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHF 493
            .|:|.:.:.|||||||||.||:.:..:..|  ::|||..|.|.|||......|:||.:...|.||
Mouse   415 YGLHHNPKVWPNPEVFDPSRFAPDSPRHSH--SFLPFSGGARNCIGKQFAMSELKVIVALTLLHF 477

  Fly   494 RVEVCERTLPEMRFDPKA-FVLTAHNGTYLRFVK 526
            .:......:||    |.| .||.:.||.||...|
Mouse   478 ELLPDPTRVPE----PLARIVLKSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6t1	NP_608457.1	CYP6-like	88..521	CDD:410679	116/466 (25%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	119/473 (25%)