Protein Alignment Ir20a and glr-8

DIOPT Version :10

• Sequence 1: NP_608456.1
• Gene: Ir20a / 33126
• FlyBaseID: FBgn0031181
• Length: 563
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 560
• Identity: 103/560 - (18%)
• Similarity: 182/560 - (32%)
• Gaps: 204/560 - (36%)

  Fly   100 NSLSHLRTVVRLLIE-VAGPDQVTLARQYLSFCLRRSMLHVELYFRDYHHSLILYSFRAFPSFEL 163
            ||:..|..::..:.| ||.|.|.:|.                   .||..:..|.:.:.|
 Worm    14 NSIRTLNNILESINEKVAHPPQTSLT-------------------SDYGDAYTLSNEKHF----- 54

  Fly   164 VMRWISVGQGVKLFLHKLDDLRGHRLR-VIPDLSPP--NTFFYRDARGDNQVT------GYLWDF 219
                            .|.:::|..|: |:|.:.||  |...:.||    .||      |.:.:.
 Worm    55 ----------------SLSEMKGRTLKMVVPAIEPPYVNYVNFSDA----AVTDKGYGPGVVMEI 99

  Fly   220 LATFAGRLNAGLEV-----------VRPSWR--------------AGSA---------SDSSYML 250
            |.....|||...|:           :..||.              ||.|         :|.:|..
 Worm   100 LKEIGKRLNLTYEILPALGSTWGEYLNGSWTGAFGQLVRGEVDLLAGGAIMEYDRSVIADLTYPF 164

  Fly   251 EYSAKGLI---------DVGLTTTLITKWNLWAIHQYTYPLLVSSWCTMLPVEKPLATPDLFGRI 306
            ::...|::         |..|..|....|.:|.|   |..:::.|....|.:...:       |.
 Worm   165 QFEPTGIMIRSPEKYEDDTLLIVTEPFSWEVWVI---TAAVILISGVIFLVMTNII-------RK 219

  Fly   307 VCPTLAMTLLLIILVTWLVFRQLRCLTRLKNSRPARIVPHLLTLLLLT---TCSAQLLSLLIFPP 368
            |...:.:|....|.|.:.:|.| :.|.....|...|::..|..|..:|   |.:..|::|.....
 Worm   220 VYEEMTVTPFESIWVFFSIFVQ-QGLPEQPRSWSCRVLVALWWLASITLSATFTGSLVALFAVDK 283

  Fly   369 YHVRIASFEDLLRGDQKILGMRNEFYNFDGAFRARYAGVFYLIDDPNELYDLRNHFNTTWAYTMP 433
            .:|                    .|.|.|...|....|.|.::.|.|             ::|
 Worm   284 TNV--------------------PFQNIDQLVRLVKQGKFEIVMDEN-------------SFT-- 313

  Fly   434 YIKWLVIKTQQRHFSK-PLFR--W---------------SKDLCFFDFMPTSVIVAP-DSIYWES 479
                   :|:....|| |::|  |               ::.:.|....|...::.| .::.:.:
 Worm   314 -------RTEMIARSKLPVYRDLWHEMIVNHKVKYVNGIARGVAFVRANPGYALLGPMATLNFYA 371

  Fly   480 IKDFTFRIHQAGLMKHW-----IRKSFY---------DMIKAG--KMSIKDYSDLETLKPLN--- 525
            ..|....:...|::..:     ::.|.|         :|::.|  :..|.||.....::.:|
 Worm   372 YSDCKVILFNDGILPVYLSIPLVKNSIYSPYFSTKIREMVERGFTQKWIADYRSYVAMQKINECN 436

  Fly   526 ---IG-----DLE----IVWRVCGAAIAVASAIFIMELLY 553
               ||     ||:    ..|...|.| .:..|:|:.|.::
 Worm   437 STTIGPKSYLDLKRAQGAFWVFLGGA-GLGLALFVGEFIF 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir20a	NP_608456.1	None
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	76/418 (18%)