DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Chl1

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_038964701.1	Gene:	Chl1 / 89828	RGDID:	620122	Length:	1224	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	83/373 - (22%)
Similarity:	134/373 - (35%)	Gaps:	94/373 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 VSNKISSVGAFEPDFVIPLENV------TIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIK 144
            :||:.:|:...:|..::|...:      |:.:|......|.          .:|...| ::.|.|
  Rat   238 ISNQANSIKQRKPKLLLPPAQIGSASSKTVLKGDTLLLECF----------AEGLPTP-QIEWSK 291

  Fly   145 ADA-----KAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTAT 204
            ..:     :|.:.|||.                  ||.|..|..:|.|.|.|..| :.:...:..
  Rat   292 LGSELPKGRATIEIHEK------------------TLKIENVSYQDRGNYRCTAN-NLLGKASHD 337

  Fly   205 LEVVI--PPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQ 267
            ..|::  ||....:..|.  :...|.:..|:|.|.|.|:|.|.| |.:|..|          :..
  Rat   338 FHVIVEEPPRWKKKPQSA--VYSTGSNGILLCEAEGEPQPTIKW-RVNGLPI----------ENH 389

  Fly   268 SVEGEM-----LTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQ-VHFHPLVQVPNQ-----LVG 321
            ...|::     ::.:.:..:....|.|.||| :..|:.....:. |...||:|..|:     :||
  Rat   390 PFPGDVMFPREISFTNLQPNHTAVYQCEASN-IHGTILANANIDVVDVVPLIQTKNEENYETVVG 453

  Fly   322 APVLTDVTLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGG 386
            ....    |.|...|||||...|:..:....:.|.||...|...        |.|:|....|.|.
  Rat   454 YSAF----LHCEYFASPKATVVWEVADETHPLEGGRYHTHENGT--------LEIERTTEEDAGS 506

  Fly   387 YKCISKNSIGDTEGTIRLYEMERPGKKILRDDDLNEVSKNEVVQKDTR 434
            |.|...|::|....|..|              |:...:|..|..|:.|
  Rat   507 YSCWVDNTMGKAVITANL--------------DIRNATKLRVFPKNPR 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	23/121 (19%)
		ig	102..195	CDD:278476	20/103 (19%)
		IG_like	219..307	CDD:214653	20/93 (22%)
		Ig	221..307	CDD:299845	19/91 (21%)
		Ig	311..404	CDD:299845	28/97 (29%)
		IG_like	327..405	CDD:214653	22/77 (29%)
Chl1	XP_038964701.1	Ig	34..125	CDD:416386
		Ig strand A	34..38	CDD:409353
		Ig strand A'	43..47	CDD:409353
		Ig strand B	52..59	CDD:409353
		Ig strand C	65..70	CDD:409353
		Ig strand C'	73..75	CDD:409353
		Ig strand D	81..84	CDD:409353
		Ig strand E	89..93	CDD:409353
		Ig strand F	104..112	CDD:409353
		Ig strand G	115..125	CDD:409353
		IgI_2_L1-CAM_like	134..224	CDD:409432
		Ig strand B	148..152	CDD:409432
		Ig strand C	162..166	CDD:409432
		Ig strand E	185..189	CDD:409432
		Ig strand F	200..205	CDD:409432
		Ig strand G	216..219	CDD:409432
		Ig	261..343	CDD:416386	21/111 (19%)
		Ig strand B	273..277	CDD:409353	0/3 (0%)
		Ig strand C	286..290	CDD:409353	0/3 (0%)
		Ig strand E	308..312	CDD:409353	2/21 (10%)
		Ig strand F	322..327	CDD:409353	2/4 (50%)
		Ig strand G	335..338	CDD:409353	0/2 (0%)
		Ig4_L1-NrCAM_like	347..434	CDD:409367	20/100 (20%)
		Ig strand B	363..367	CDD:409367	1/3 (33%)
		Ig strand C	376..380	CDD:409367	2/4 (50%)
		Ig strand E	399..403	CDD:409367	0/3 (0%)
		Ig strand F	413..418	CDD:409367	2/4 (50%)
		Ig strand G	426..429	CDD:409367	0/2 (0%)
		Ig	447..524	CDD:416386	24/88 (27%)
		Ig strand A'	447..451	CDD:409353	0/3 (0%)
		Ig strand B	454..463	CDD:409353	2/12 (17%)
		Ig strand C	469..474	CDD:409353	1/4 (25%)
		Ig strand C'	477..480	CDD:409353	0/2 (0%)
		Ig strand D	485..490	CDD:409353	2/4 (50%)
		Ig strand E	491..498	CDD:409353	2/14 (14%)
		Ig strand F	505..513	CDD:409353	3/7 (43%)
		Ig strand G	516..524	CDD:409353	2/7 (29%)
		Ig	528..627	CDD:416386	4/13 (31%)
		Ig strand A	528..534	CDD:409353	1/5 (20%)
		Ig strand A'	537..542	CDD:409353	2/4 (50%)
		Ig strand B	545..553	CDD:409353
		Ig strand C	564..568	CDD:409353
		Ig strand D	583..586	CDD:409353
		Ig strand E	589..593	CDD:409353
		Ig strand F	602..609	CDD:409353
		Ig strand G	616..620	CDD:409353
		FN3	627..716	CDD:238020
		fn3	730..811	CDD:394996
		FN3	832..926	CDD:238020
		FN3	931..1026	CDD:238020
		Bravo_FIGEY	1120..1201	CDD:404722
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100