DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-beta and zgc:153911

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001070783.1	Gene:	zgc:153911 / 768172	ZFINID:	ZDB-GENE-061013-174	Length:	288	Species:	Danio rerio

Alignment Length:	279	Identity:	52/279 - (18%)
Similarity:	94/279 - (33%)	Gaps:	76/279 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 ITWRR--------EDGREIIARNGSHQKTKAQSVEGEM------LTLSKITRSEMGAYMC-IASN 293
            |||:|        ...|:.:.|...|..::......||      |.|.|:|:.:.|.|.| |::|
Zfish    57 ITWQRGLDVVHSFYYSRDQLDRQNPHYVSRTSLFIQEMQRGNASLKLDKVTQRDAGVYTCSISTN 121

  Fly   294 GVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTD-VTLICNVEAS-PKAINYWQRENGEMIIAGD 356
                :.|::....|:...|...|.  :...:||| |.|:...:.. |.....|..||.::.....
Zfish   122 ----SGSQKKSFAVNIAALYSEPR--LQFSMLTDGVNLLVTSDGGYPSPTLQWLMENSDITNQTQ 180

  Fly   357 RYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEMERPGKKILRDDDLN 421
            .:...:....:|.:...:.:..:.:|                                    .|.
Zfish   181 THLRQDTSTGLYIVSSWIKLSDVSNS------------------------------------SLT 209

  Fly   422 EVSKNEVVQKDTRSEDGSRNLNGRLYKDRAPDQHPASGSDQLLGRGTMRLIGTFLLALLVLFTAL 486
            .:..|:.:.:|.|.|.       :|..|:...|.....|:..:    :..:...|||:::||...
Zfish   210 FILHNKPLGQDIRREI-------QLSSDKIEKQEENRCSECFI----LIPVALLLLAMVLLFVFF 263

  Fly   487 ------AEAGPTTLSCRTK 499
                  ||....:.|..||
Zfish   264 IKRRRKAEKSKQSSSSETK 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352
		ig	102..195	CDD:278476
		IG_like	219..307	CDD:214653	19/77 (25%)
		Ig	221..307	CDD:299845	19/77 (25%)
		Ig	311..404	CDD:299845	13/94 (14%)
		IG_like	327..405	CDD:214653	9/79 (11%)
zgc:153911	NP_001070783.1	V-set	28..122	CDD:284989	18/68 (26%)
		IG_like	35..133	CDD:214653	20/79 (25%)
		Ig	<156..221	CDD:299845	8/100 (8%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000