DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and lsamp

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001034921.1	Gene:	lsamp / 664692	ZFINID:	ZDB-GENE-090108-1	Length:	333	Species:	Danio rerio

Alignment Length:	337	Identity:	92/337 - (27%)
Similarity:	143/337 - (42%)	Gaps:	73/337 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 FEPDFVIPLE------NVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIH 154
            ||...||.:|      |:||.||......|.|::    :||        ||||:  :...|:...
Zfish    20 FEGFPVISVESQRSTDNITIRQGDTTVIRCYVDD----KVS--------KVAWL--NRSNIIFAG 70

  Fly   155 EHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEV--VIPPDIINEE 217
            |...:.:.|:.:.......::|.|:.|.:.|.|.|.|.:.|   |.|:.|.:|  ::....|..:
Zfish    71 EDKWSLDPRVELVTQGQLEYSLRIQKVDVFDEGPYTCSIQT---KQQSKTSQVYLIVQVPAIIYK 132

  Fly   218 TSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVE-GEMLTLSKITR 281
            .|.|:.|.||.:..|.|.|.|.|.|.||||        ..|.|     |:::: ||.|.:|.:.|
Zfish   133 VSEDITVNEGSNVALTCLANGRPDPAITWR--------LLNPS-----AEALDVGEYLEISGVVR 184

  Fly   282 SEMGAYMCIASNGVPPTVSKRMKLQVHFHPL---VQVPNQLVG-APVLTDVTLICNVEASPKAIN 342
            |:.|.|.|.|||.|.....|.:.:.|::.|.   |:.....|| |.||.     |...|.|:...
Zfish   185 SQAGRYECKASNDVSTPDVKYVNVVVNYPPYIKDVRSSETAVGQAGVLH-----CEASAVPQPEF 244

  Fly   343 YWQRENGEMI--------IAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTE 399
            .|.|:...:.        ::|.|              .:|.:..:...|:|.|.|::.|.:|...
Zfish   245 EWYRDERRLSSSQSLTIQVSGSR--------------TVLVVANVTEEDYGNYTCVATNRLGVHN 295

  Fly   400 GTIRLYEMERPG 411
            .::.||   :||
Zfish   296 ASVFLY---KPG 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	31/118 (26%)
		ig	102..195	CDD:278476	25/98 (26%)
		IG_like	219..307	CDD:214653	32/88 (36%)
		Ig	221..307	CDD:299845	31/86 (36%)
		Ig	311..404	CDD:299845	21/104 (20%)
		IG_like	327..405	CDD:214653	14/85 (16%)
lsamp	NP_001034921.1	Ig	34..124	CDD:299845	28/106 (26%)
		IG_like	36..124	CDD:214653	28/104 (27%)
		IG_like	134..197	CDD:214653	29/75 (39%)
		IGc2	141..199	CDD:197706	27/70 (39%)
		I-set	213..300	CDD:254352	21/105 (20%)
		Ig	231..298	CDD:143165	16/85 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010