DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Skint1

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001096132.1	Gene:	Skint1 / 639781	MGIID:	3649627	Length:	364	Species:	Mus musculus

Alignment Length:	235	Identity:	53/235 - (22%)
Similarity:	100/235 - (42%)	Gaps:	53/235 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   198 MKMQTATLEVVIPPDIINEETSGDMMVPEGGSAKLVCRARGHPKP----KITWRR---------- 248
            ::|.||:.|    |.|:| ...|.::...||:.:|.|:. ..|:.    :|.|.|
Mouse    18 LQMVTASSE----PFIVN-GLEGPVLASLGGNLELSCQL-SPPQQAQHMEIRWFRNLYTEPVHLY 76

  Fly   249 EDGR----EIIARNGSHQKTKAQSV-EGEM-LTLSKITRSEMGAYMCIASNG---------VPPT 298
            .||:    |||::.....:.....: ||:: |.:..:|..:.|:|.|:..:|         |..|
Mouse    77 RDGKDMFGEIISKYVERTELLKDGIGEGKVTLRIFNVTVDDDGSYHCVFKDGDFYEEHITEVKIT 141

  Fly   299 VSKRMKLQVHFHPLVQVPNQLVGAPVLTDVTLICNVEA-SPKAINYWQRENGEMIIAGDRYALTE 362
             :..:::|:|.||           |....|.:.|:... .|:.:..|:...||:|.|..: :.::
Mouse   142 -AINLQVQIHVHP-----------PNTKGVIVECHSGGWFPRPLMQWRDRRGEVIPAASK-SHSQ 193

  Fly   363 KENNMYAIEMILHIKRLQSSDFGGYKCISKNSI-GDTEGT 401
            ..:.::.:::.|.|   ..|.|....|..:|.: |..|.|
Mouse   194 GRDKLFNMKISLLI---SESFFQKVICCLQNPLTGQEERT 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	4/10 (40%)
		ig	102..195	CDD:278476
		IG_like	219..307	CDD:214653	24/116 (21%)
		Ig	221..307	CDD:299845	23/114 (20%)
		Ig	311..404	CDD:299845	19/93 (20%)
		IG_like	327..405	CDD:214653	17/77 (22%)
Skint1	NP_001096132.1	IGv domain	27..141		26/115 (23%)
		IG_like	35..140	CDD:214653	23/105 (22%)
		Ig_MOG_like	42..141	CDD:143190	22/99 (22%)
		IGc domain	142..228		20/100 (20%)
		transmembrane domain 1	247..269
		transmembrane domain 2	282..304
		transmembrane domain 3	326..348
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000