DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and kirrel3b

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_021323594.1	Gene:	kirrel3b / 572369	ZFINID:	ZDB-GENE-100713-3	Length:	795	Species:	Danio rerio

Alignment Length:	355	Identity:	76/355 - (21%)
Similarity:	133/355 - (37%)	Gaps:	87/355 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 IDLTVSNKISSVGA-------FEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAK 139
            :...|:|.:.|...       |.|......:::.:..|.||.|.|.        .:|:.|   ..
Zfish   293 VSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCA--------WTGNPS---LT 346

  Fly   140 VAWIKADAKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTAT 204
            :.|:|..:..:|: :|:::|                  ::.|:.||||||:|:....  ::..|.
Zfish   347 IVWMKRGSGVVLS-NENILT------------------LKSVRQEDAGKYVCRAVVP--RVGAAE 390

  Fly   205 LEVVI----PPDIINEETSGDMMVPEGGSAKLVCRARGHPKP-KITWRREDGREIIARNGSHQKT 264
            .||.:    ||.|.:.:|.   ..|.|...::.|..|..|.| :|.|   ..:|.:..:|:..:.
Zfish   391 KEVSLTVNGPPTISSTQTH---QAPHGEKGQIKCFIRSTPPPDRIAW---SWKETVLESGTSGRY 449

  Fly   265 KAQSVEGEMLTLSKITRSEM------GAYMCIASNGV-PPTVSKRMKLQVHFH---PLVQVPNQL 319
            ..::|..|...||.:|.|.:      ..|.|.|.|.. ..|...|:|.|....   |:..:....
Zfish   450 TVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGGSQDSLPVAVIIGVA 514

  Fly   320 VGAPVLTDVTL------------------ICNVEAS------PKAINYWQRENGEMIIAGDRYAL 360
            |||.|...|.:                  :|..:|.      |.:|...|||....|...:...:
Zfish   515 VGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTEDAHLVMPTLPTSICAQQRELASKIKTENLKGV 579

  Fly   361 TEKENNMYAIEMIL--HIKRLQSSDFGGYK 388
            ...:|:: .:|::.  |....:|.:..|.|
Zfish   580 VSAKNDI-RVEIVHKDHNAARESEEHSGMK 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	24/110 (22%)
		ig	102..195	CDD:278476	20/92 (22%)
		IG_like	219..307	CDD:214653	23/95 (24%)
		Ig	221..307	CDD:299845	23/93 (25%)
		Ig	311..404	CDD:299845	20/104 (19%)
		IG_like	327..405	CDD:214653	15/88 (17%)
kirrel3b	XP_021323594.1	IG_like	35..124	CDD:214653
		Ig2_KIRREL3-like	146..227	CDD:143236
		Ig_2	235..312	CDD:316418	3/18 (17%)
		I-set	316..397	CDD:333254	24/112 (21%)
		Ig5_KIRREL3	399..496	CDD:143306	26/102 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910