DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and PSG6

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_002773.1	Gene:	PSG6 / 5675	HGNCID:	9523	Length:	435	Species:	Homo sapiens

Alignment Length:	294	Identity:	61/294 - (20%)
Similarity:	101/294 - (34%)	Gaps:	83/294 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 ITNNDRLSVQHN---DYNTWTLNIRGVKMEDAGKYMCQV-------NTDPMKMQTATLEVVIP-P 211
            :.|...|.:.|.   .....||.:.||....||.|.|::       .:||:   |..|...:| |
Human   180 LLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPV---TLNLLPKLPMP 241

  Fly   212 DI----INEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGE 272
            .|    :|.....|::.       ..|..:......|.|.......:..|       ..:.:|..
Human   242 YITINNLNPREKKDVLA-------FTCEPKSRNYTYIWWLNGQSLPVSPR-------VKRPIENR 292

  Fly   273 MLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLT------DVTLI 331
            :|.|..:||:|.|.|.|...:......|..:.|.|.:.|  .:|...   |..|      ::.|.
Human   293 ILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGP--DLPRIY---PSFTYYRSGENLDLS 352

  Fly   332 CNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIG 396
            |..:::|.|...| ..||:..::|.:                |.|.::.::..|.|.|..:||
Human   353 CFADSNPPAEYSW-TINGKFQLSGQK----------------LFIPQITTNHSGLYACSVRNS-- 398

  Fly   397 DTEGTIRLYEMERPGKKILRDDDLNEVSKNEVVQ 430
                        ..||         |:||:.:|:
Human   399 ------------ATGK---------EISKSMIVK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	15/60 (25%)
		ig	102..195	CDD:278476	11/46 (24%)
		IG_like	219..307	CDD:214653	16/87 (18%)
		Ig	221..307	CDD:299845	16/85 (19%)
		Ig	311..404	CDD:299845	19/98 (19%)
		IG_like	327..405	CDD:214653	15/77 (19%)
PSG6	NP_002773.1	Ig_CEACAM_D1	36..139	CDD:143251
		Cell attachment site. /evidence=ECO:0000255	126..128
		Ig	147..235	CDD:299845	14/57 (25%)
		Ig	241..328	CDD:299845	19/100 (19%)
		IG_like	259..327	CDD:214653	15/74 (20%)
		Ig_2	334..412	CDD:290606	24/121 (20%)
		IG_like	338..398	CDD:214653	15/76 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000