DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and olfml2ba

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001038314.1	Gene:	olfml2ba / 557997	ZFINID:	ZDB-GENE-041014-329	Length:	883	Species:	Danio rerio

Alignment Length:	423	Identity:	84/423 - (19%)
Similarity:	132/423 - (31%)	Gaps:	127/423 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 AWIKADAKAILAIHEHVITNNDRLSV-----QH------NDYNTWTLNIRGVKMEDAGKYMCQVN 194
            |...|..|:.|.:.|....|||.|.|     :|      .||:.......|   .|.|   |:..
Zfish    15 ALTSAAPKSHLRLEEKTKDNNDTLQVEIDNQEHILSQLLGDYDKVKALSEG---SDCG---CKCV 73

  Fly   195 TDPMKMQT--------ATLEVVIPPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDG 251
            ..|:....        ||     |.|....||     :..|...|..|.|   |...:.....|.
Zfish    74 VRPLSASACQRIREGHAT-----PQDFYTVET-----ITSGPHCKCACIA---PPSALNPCEGDF 125

  Fly   252 REIIARNGSHQKTKAQSV----EG-----EMLTLSKITRSEMGAYMCIASNGVPPTVSKRM---K 304
            |....|.......|..::    ||     ::|.|..:|...:...         .|:.|.:   :
Zfish   126 RLKKLRQAGKDNIKLSTILELLEGSFYGMDLLKLHSVTTKILDRM---------DTIEKMVLNNQ 181

  Fly   305 LQVHFHPLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENGEMIIAGDRYALTEKENNMYA 369
            .:...:.:...||     |.|:        .:||..:        ..:|...|.:|.|:.:...|
Zfish   182 TEEKLNTISTSPN-----PQLS--------TSSPTTL--------PSVIQEKRTSLREQNDEAAA 225

  Fly   370 IEMILHIKRLQSSDFGGYKCISKNSIGD--------TEGTIRLYEMERPGKK-----------IL 415
            .:.:.:...|:.:....|:   :..:||        .:.|..|.|.|:.|:|           ..
Zfish   226 FQHMEYYSVLKCTQQSKYE---EKFVGDILNSGSDLNKATTALQEQEQQGRKKQPKITVRGITYY 287

  Fly   416 RDDDLNEVSKNEVVQKDTRSEDGSRNLNGRLYKDRAPDQHPASGSDQLLGRGTMRLIGTFLLALL 480
            |.|.::|:             |..:||:..|..|...|..    :|:.|.|...|.....:.|..
Zfish   288 RSDPVDEM-------------DSEKNLDDNLSGDSPIDLF----ADEQLLRHKARHFRPVIKAWS 335

  Fly   481 VLFTALAEAGPTTLSCRTKGGRQKKAKETSWNG 513
            |        .|.|.|..:|||...|..:....|
Zfish   336 V--------RPKTKSEISKGGDAPKKHQNPLMG 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	20/86 (23%)
		ig	102..195	CDD:278476	17/64 (27%)
		IG_like	219..307	CDD:214653	16/99 (16%)
		Ig	221..307	CDD:299845	16/97 (16%)
		Ig	311..404	CDD:299845	16/100 (16%)
		IG_like	327..405	CDD:214653	12/85 (14%)
olfml2ba	NP_001038314.1	PHA03255	450..>584	CDD:165513
olfml2ba	NP_001038314.1	OLF	625..875	CDD:280371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000