DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and iglon5

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001017775.2	Gene:	iglon5 / 550472	ZFINID:	ZDB-GENE-050417-297	Length:	332	Species:	Danio rerio

Alignment Length:	361	Identity:	88/361 - (24%)
Similarity:	152/361 - (42%)	Gaps:	76/361 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 GAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVI 158
            ||...:|....:|:|:.:|......|.::....|:            ||:  :...||.......
Zfish    23 GAQAAEFGHLPDNITVLEGESVVLRCKIDEEVTHK------------AWL--NRSNILFTGTDKW 73

  Fly   159 TNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMC--QVNTDPMKMQTA--TLEVVIPPDIINEETS 219
            :.:.|:|:::|:.:.:::.|..|.:.|.|.|.|  |....|   :||  .|.|.:|..|:|  .|
Zfish    74 SLDSRVSLENNNNSDFSIRIERVMVADEGPYTCSFQARNKP---RTAHVYLIVQVPARIVN--IS 133

  Fly   220 GDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEM 284
            .|..|.||....|.|.|.|.|:|.|||:  |.:..:..            |||.|.:::|.|.:.
Zfish   134 QDKSVNEGEDVNLFCLAVGRPEPTITWK--DFKYGLLN------------EGEFLEITEIKRHQA 184

  Fly   285 GAYMCIASNGVPPTVSKRMKLQVHFHPLV----QVPNQLVGAPVLTDVTLICNVEASPKAINYWQ 345
            ..:.||.:|||.|..::::|:.|::.|::    .:|.| ||...:    |.|...|.|.|...|.
Zfish   185 EDFECITNNGVAPPDTRKVKVTVNYPPIITDVKNMPAQ-VGKTAI----LRCEAMAVPTASFEWY 244

  Fly   346 RENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRLYEMERP 410
            |::...:.:.:...:..::.     ..:|....:....||.|.|.:.|.:|.:..::.|:   ||
Zfish   245 RDDRRPVESDNTLKIKNEKT-----RSLLLFTNVTEKHFGNYTCFASNRLGASNASMLLF---RP 301

  Fly   411 GKKILRDDDLNEVSKNEVVQKDTRSEDGSRNLNGRL 446
            |...                      .|:.:|||||
Zfish   302 GAVY----------------------GGAASLNGRL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	25/114 (22%)
		ig	102..195	CDD:278476	19/94 (20%)
		IG_like	219..307	CDD:214653	28/87 (32%)
		Ig	221..307	CDD:299845	27/85 (32%)
		Ig	311..404	CDD:299845	19/96 (20%)
		IG_like	327..405	CDD:214653	14/77 (18%)
iglon5	NP_001017775.2	IG_like	33..123	CDD:214653	23/106 (22%)
		Ig	35..123	CDD:299845	23/104 (22%)
		Ig	125..>183	CDD:299845	24/73 (33%)
		I-set	128..207	CDD:254352	30/94 (32%)
		IG_like	217..298	CDD:214653	18/90 (20%)
		ig	223..296	CDD:278476	16/81 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576289
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850