DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-beta and Icosl

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:XP_036011782.1 Gene:Icosl / 50723 MGIID:1354701 Length:347 Species:Mus musculus


Alignment Length:280 Identity:56/280 - (20%)
Similarity:96/280 - (34%) Gaps:86/280 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 VGLGT----------GTGTGSGCGPAIRWQLLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLEN 106
            |.|||          .:|..||.|       |.||||.:   |..::..:.|||.          
Mouse    84 VSLGTRQPVWKKLHVSSGFFSGLG-------LFLLLLSS---LCAASAETEVGAM---------- 128

  Fly   107 VTIAQGRDATFTCVVN-----NLGG----HRVSGDGSSA----PAKVAWIKADAKAILAIHEHVI 158
                .|.:...:|:..     ||.|    .::.....|.    |.|...|..|:.         .
Mouse   129 ----VGSNVVLSCIDPHRRHFNLSGLYVYWQIENPEVSVTYYLPYKSPGINVDSS---------Y 180

  Fly   159 TNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEVVIPPDIINEETSGDMM 223
            .|...||:.......::|.::.|..:|..::.|:|     .|.|||..|.|..:::....:.:..
Mouse   181 KNRGHLSLDSMKQGNFSLYLKNVTPQDTQEFTCRV-----FMNTATELVKILEEVVRLRVAANFS 240

  Fly   224 VP---------EGGSAKLVCRAR-GHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSK 278
            .|         .|......|.:: |:|:|.:.|.......:|       .|..|:        :.
Mouse   241 TPVISTSDSSNPGQERTYTCMSKNGYPEPNLYWINTTDNSLI-------DTALQN--------NT 290

  Fly   279 ITRSEMGAYMCIASNGVPPT 298
            :..:::|.|..|::..:|.|
Mouse   291 VYLNKLGLYDVISTLRLPWT 310

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352 23/123 (19%)
ig 102..195 CDD:278476 18/105 (17%)
IG_like 219..307 CDD:214653 15/90 (17%)
Ig 221..307 CDD:299845 15/88 (17%)
Ig 311..404 CDD:299845
IG_like 327..405 CDD:214653
IcoslXP_036011782.1 IgV_B7-H2 123..236 CDD:409529 27/140 (19%)
Ig strand B 133..137 CDD:409529 0/3 (0%)
Ig strand C 151..155 CDD:409529 0/3 (0%)
Ig strand E 196..200 CDD:409529 1/3 (33%)
Ig strand F 210..215 CDD:409529 1/4 (25%)
Ig strand G 228..231 CDD:409529 0/2 (0%)
Ig 241..328 CDD:416386 15/85 (18%)
Ig strand B 256..263 CDD:409353 1/6 (17%)
Ig strand C 269..276 CDD:409353 2/6 (33%)