DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and dpr15

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001287299.1	Gene:	dpr15 / 41473	FlyBaseID:	FBgn0037993	Length:	662	Species:	Drosophila melanogaster

Alignment Length:	295	Identity:	60/295 - (20%)
Similarity:	105/295 - (35%)	Gaps:	46/295 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VKESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLGTGTGTGS----GCGPA 67
            :..:|::...::.:.|.....|.:..|.....::.|....|.:.:...||..|...    |..||
  Fly    94 ISNNGDQRLRLTAALEANLIMSNRNVQEQHSYRITQDNATSAASIAPNGTAFGDAPSIPIGVAPA 158

  Fly    68 IRWQLLLLLLLGNCID-----------LTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVV 121
            ..          ..||           .|....:::.....|..:...:.:....|..|...|.|
  Fly   159 TT----------TTIDPATTTPTTTTRRTTRRPVATTTLKPPPTIDDYQTIISQAGTHAYLPCNV 213

  Fly   122 NNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDRL-SVQHNDYNTWTLNIRGVKMED 185
            ..|           ....::|::.....||.:.:.....:.|. ||...:...|:|.|:.|:::|
  Fly   214 KQL-----------VKKPISWLRMRDGHILTVDQTTFIADQRFQSVFSPNPERWSLQIKYVQLKD 267

  Fly   186 AGKYMCQVNTDPMKMQTATLEVVIP-PDIINEETSGDMMVPEGGSAKLVCRARGHPKPK--ITWR 247
            .|.|.|||:|:|.......|.:|.| .::|.|.|   ..|..|...||.|......:|.  |.|.
  Fly   268 EGTYECQVSTEPKASAIVHLRIVEPKTELIGEST---RHVKAGSQVKLRCIISQALEPPLFINWF 329

  Fly   248 REDGREIIARNGSHQKTKAQSVE--GEMLTLSKIT 280
            ... ::|...|....:|:.:.::  .|:.|.|..|
  Fly   330 YNQ-KQIYLHNRRGWRTEIERIDLPAEVPTTSTTT 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	25/111 (23%)
		ig	102..195	CDD:278476	21/93 (23%)
		IG_like	219..307	CDD:214653	15/66 (23%)
		Ig	221..307	CDD:299845	15/64 (23%)
		Ig	311..404	CDD:299845
		IG_like	327..405	CDD:214653
dpr15	NP_001287299.1	IG_like	197..289	CDD:214653	24/102 (24%)
dpr15	NP_001287299.1	V-set	204..290	CDD:284989	24/96 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810