DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and dpr17

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001287297.1	Gene:	dpr17 / 41470	FlyBaseID:	FBgn0051361	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	314	Identity:	73/314 - (23%)
Similarity:	112/314 - (35%)	Gaps:	92/314 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KESGERIADISCSQEHTTKFSPKLSQVAKHRKLAQLEIASGSGLVGLGTGTGTGSGCGPAIRWQL 72
            |.|.|.:. :|..::....|:.:.|.:|.||                    ..|.|.|.|:|..|
  Fly   365 KTSSEAVT-MSPEEQRRQMFNEQHSYLAAHR--------------------DGGDGAGSAVRRNL 408

  Fly    73 LLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAP 137
                                        .:|:.|:|...|..|...|.:     ||:|      .
  Fly   409 ----------------------------TMPVLNITAQMGNHAYMPCQI-----HRLS------D 434

  Fly   138 AKVAWIKADAKAILAIHEHVITNNDRL-SVQHNDYN-TWTLNIRGVKMEDAGKYMCQVNTDPMKM 200
            ..|:|::.....|:::.|.....::|. |:...|:: ||:|.|:.|:..|||.|.||:.|:|...
  Fly   435 KPVSWVRMRDNHIISVDETTFIADERFQSIYQEDHDYTWSLQIKYVEPSDAGWYECQMATEPKLS 499

  Fly   201 QTATLEVVIPPDIINEETSGDM--MVPEGGSAKLVCRARGHPKP-----------KIT------- 245
            ....|::|.|    ..|..||.  .|..|....|.|..||...|           ||:
  Fly   500 AKVHLQIVKP----KTELIGDQSRFVKAGSKVALHCIVRGTLDPPKYIIWFRGQKKISDSDERTG 560

  Fly   246 WRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTV 299
            |..:..|.|....|.:|.|...      |.:..:.:.:.|.|.|..||.|..:|
  Fly   561 WYTQLDRNIFGTVGDNQNTIGS------LIIPLVRKEDSGNYTCQPSNSVSVSV 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	30/112 (27%)
		ig	102..195	CDD:278476	27/94 (29%)
		IG_like	219..307	CDD:214653	25/101 (25%)
		Ig	221..307	CDD:299845	24/99 (24%)
		Ig	311..404	CDD:299845
		IG_like	327..405	CDD:214653
dpr17	NP_001287297.1	IG_like	414..491	CDD:214653	24/87 (28%)
		Ig	415..507	CDD:299845	28/102 (27%)
		IG_like	521..612	CDD:214653	23/94 (24%)
		IGc2	524..605	CDD:197706	20/86 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I12107
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810