Protein Alignment DIP-beta and IGLON5

DIOPT Version :10

• Sequence 1: NP_001138225.1
• Gene: DIP-beta / 33125
• FlyBaseID: FBgn0259245
• Length: 555
• Species: Drosophila melanogaster
• Sequence 2: NP_001094842.1
• Gene: IGLON5 / 402665
• HGNCID: 34550
• Length: 336
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 95/361 - (26%)
• Similarity: 150/361 - (41%)
• Gaps: 71/361 - (19%)

  Fly    66 PAIRWQLLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVS 130
            |..|.:||....|...  ..:|..:.|...   :|..|.:|.|:.:|.:||.:|.::.   |
Human     6 PGARLRLLAAAALAGL--AVISRGLLSQSL---EFNSPADNYTVCEGDNATLSCFIDE---H--- 59

  Fly   131 GDGSSAPAKVAWIKADAKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNT 195
                  ..:|||:  :...||.......|::.|:.:..|....:::.|..|.:.|.|.|.|...|
Human    60 ------VTRVAWL--NRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQT 116

  Fly   196 DPMKMQTATLEVV-IPPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNG 259
            ......|....:| :|..|:|  .|..:.|.|||:..|:|.|.|.|:|.:|||:       .|:|
Human   117 RHQPYTTQVYLIVHVPARIVN--ISSPVTVNEGGNVNLLCLAVGRPEPTVTWRQ-------LRDG 172

  Fly   260 SHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPV 324
            .       :.|||:|.:|.|.|.:.|.|.|:..|||......|..|....:|           |.
Human   173 F-------TSEGEILEISDIQRGQAGEYECVTHNGVNSAPDSRRVLVTVNYP-----------PT 219

  Fly   325 LTDVT-----------LICNVEASPKAINYWQRENGEMIIAGDRYAL---TEKENNMYAIEMILH 375
            :||||           |.|...|.|.|...|.::: .::.:|....|   ||:..:|      |.
Human   220 ITDVTSARTALGRAALLRCEAMAVPPADFQWYKDD-RLLSSGTAEGLKVQTERTRSM------LL 277

  Fly   376 IKRLQSSDFGGYKCISKNSIGDTEGTIRLYEMERPG 411
            ...:.:..:|.|.|.:.|.:|.:..::||.   |||
Human   278 FANVSARHYGNYTCRAANRLGASSASMRLL---RPG 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	Ig	98..209	CDD:472250	26/111 (23%)
		Ig strand B	115..119	CDD:409353	2/3 (67%)
		Ig strand C	139..143	CDD:409353	2/3 (67%)
		Ig strand E	174..178	CDD:409353	0/3 (0%)
		Ig strand F	188..193	CDD:409353	2/4 (50%)
		Ig strand G	202..205	CDD:409353	1/2 (50%)
		Ig	211..307	CDD:472250	33/95 (35%)
		Ig strand B	230..234	CDD:409353	1/3 (33%)
		Ig strand C	243..247	CDD:409353	1/3 (33%)
		Ig strand E	272..276	CDD:409353	2/3 (67%)
		Ig strand F	286..291	CDD:409353	2/4 (50%)
		Ig strand G	300..303	CDD:409353	0/2 (0%)
		IG_like	327..405	CDD:214653	21/91 (23%)
		Ig strand B	328..332	CDD:409353	3/14 (21%)
		Ig strand C	341..346	CDD:409353	1/4 (25%)
		Ig strand E	365..376	CDD:409353	2/10 (20%)
		Ig strand F	386..391	CDD:409353	2/4 (50%)
		Ig strand G	399..402	CDD:409353	0/2 (0%)
IGLON5	NP_001094842.1	Ig strand G	122..125	CDD:409382	1/2 (50%)
		Ig_3	134..199	CDD:464046	28/80 (35%)
		Ig_3	217..295	CDD:464046	21/95 (22%)
		Ig	41..129	CDD:472250	23/101 (23%)
		Ig strand B	50..54	CDD:409382	2/3 (67%)
		Ig strand C	62..66	CDD:409382	2/3 (67%)
		Ig strand E	95..99	CDD:409382	0/3 (0%)
		Ig strand F	109..114	CDD:409382	2/4 (50%)