DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and fipi

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	274	Identity:	62/274 - (22%)
Similarity:	116/274 - (42%)	Gaps:	42/274 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 IHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEVVIPPDIINEE 217
            |.||    ..|:.::........:....:.:.|.|.:.|:....  .:.:.:.::::...|...|
  Fly    65 IREH----KGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADG--SLHSKSFDLIVYQKITFTE 123

  Fly   218 TSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRS 282
            .:..|.|.||..|.::|..:|.|:|.:|| ..:|:.|.|......|.:   :..:.|.::|:|::
  Fly   124 NATVMTVKEGEKATILCEVKGEPQPNVTW-HFNGQPISAGAADDSKFR---ILADGLLINKVTQN 184

  Fly   283 EMGAYMCIA--SNGVPPTVSKRMKLQVHFH-------PLVQVPNQLVGAPVLTDVTLICNVEASP 338
            :.|.|.|.|  .|.:...:.:|..|....|       |.|.:....:..    ..||:|...|.|
  Fly   185 DTGEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYAYING----TATLMCEALAEP 245

  Fly   339 KAINYWQRENGEMIIAGDRYALTEKENNMYAIE-------MILHIKRLQSSDFGGYKCISKNSIG 396
            .|...|.|::.::          ...|.:|.|:       :.:|:  |.:|.|..|:|.::|.:|
  Fly   246 PANFTWYRKHNKL----------HSNNRLYTIQSDSYWSSLTIHV--LNTSAFDNYRCRARNDLG 298

  Fly   397 DTEGTIRLYEMERP 410
            ..|.|.||.:.|:|
  Fly   299 TIERTTRLEQGEKP 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	7/55 (13%)
		ig	102..195	CDD:278476	7/41 (17%)
		IG_like	219..307	CDD:214653	25/89 (28%)
		Ig	221..307	CDD:299845	25/87 (29%)
		Ig	311..404	CDD:299845	23/99 (23%)
		IG_like	327..405	CDD:214653	22/84 (26%)
fipi	NP_787975.1	IG_like	33..115	CDD:214653	7/55 (13%)
		I-set	128..202	CDD:254352	23/77 (30%)
		Ig	133..>193	CDD:299845	18/63 (29%)
		IG_like	228..307	CDD:214653	22/94 (23%)
		Ig	235..305	CDD:143165	21/81 (26%)
		FN3	312..415	CDD:238020	1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442808
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840