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Protein Alignment DIP-beta and HSPG2

DIOPT Version :10

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_011539620.1	Gene:	HSPG2 / 3339	HGNCID:	5273	Length:	4574	Species:	Homo sapiens

Alignment Length:	315	Identity:	78/315 - (24%)
Similarity:	124/315 - (39%)	Gaps:	74/315 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 TIAQGRDATFTCVVNNLGGHRVSGDGSSAPA-KVAWIKADAKAILAIHEHVITNNDRLSVQHNDY 171
            ::..|.|.||.|...           |.:|| .:.|.:        :|      |.:|..:..|:
Human  1965 SVRPGADVTFICTAK-----------SKSPAYTLVWTR--------LH------NGKLPTRAMDF 2004

  Fly   172 NTWTLNIRGVKMEDAGKYMCQ-VNTDPMKMQTATLEVVIPPDIINEETSGDMMVP---------- 225
            | ..|.||.|::.|||.|:|. .|...|...||||.|         :.||.:..|
Human  2005 N-GILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHV---------QASGTLSAPVVSIHPPQLT 2059

  Fly   226 --EGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEMGAYM 288
              .|..|:..|.|.|.|.|.:.|....|.::.|        ||| :.|.:|.|..:..::...|:
Human  2060 VQPGQLAEFRCSATGSPTPTLEWTGGPGGQLPA--------KAQ-IHGGILRLPAVEPTDQAQYL 2115

  Fly   289 CIASNGVPPTVSKRMKLQVHFH----PLVQVPNQLVGAPVLTDVTLICNVEASPKAINYWQRENG 349
            |.|.:.....|::.:   :|.|    |.|||..:.........|.|.|.....|.|...|::|.|
Human  2116 CRAHSSAGQQVARAV---LHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGG 2177

  Fly   350 EMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRL 404
            .:    ...|.:|:.:    |..:| |..:.::|.|.|.|::.:..|..:..|::
Human  2178 SL----PPQARSERTD----IATLL-IPAITTADAGFYLCVATSPAGTAQARIQV 2223

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.