DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Skint2

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_017175754.1	Gene:	Skint2 / 329919	MGIID:	3649629	Length:	404	Species:	Mus musculus

Alignment Length:	213	Identity:	50/213 - (23%)
Similarity:	90/213 - (42%)	Gaps:	47/213 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 MMVPEGGSAKLVCRARGHPKP----KITWRREDGRE--IIARNGS--HQKTKAQSVE-------- 270
            ::.|.||:.:|.|:. ..|:.    :|.|.|...||  .:.|||.  |.:|.::.||
Mouse    38 VLAPLGGNVELSCQL-SPPQQAQHMEIRWFRNRYREPVYLYRNGKDLHGETISKYVERTELLKDD 101

  Fly   271 ---GEM-LTLSKITRSEMGAYMCIASNG---------VPPTVSKRMKLQVHFHPLVQVPNQLVGA 322
               |:: |.:.|:|..:.|:|.|:...|         :..|.:..:     .:.|:|.||
Mouse   102 IGKGKVTLRIFKLTADDDGSYHCVFKVGEFYEEHITEIKVTATSSV-----MYILMQPPN----- 156

  Fly   323 PVLTDVTLICNVEA-SPKAINYWQRENGEMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGG 386
              :..|.|.|:... .|:....|:...|.:|.|..: |.::.||.::.:.|.|.|   ::|....
Mouse   157 --IKGVMLECHSGGWFPQPHMEWRDNKGNIIPATSK-AHSQDENKLFNMTMTLLI---EASSHRS 215

  Fly   387 YKCISKNSIGDTEGTIRL 404
            ..|..:|.:...|.:|.:
Mouse   216 ITCYLQNLLTHQEESISI 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352
		ig	102..195	CDD:278476
		IG_like	219..307	CDD:214653	27/113 (24%)
		Ig	221..307	CDD:299845	27/113 (24%)
		Ig	311..404	CDD:299845	23/93 (25%)
		IG_like	327..405	CDD:214653	19/79 (24%)
Skint2	XP_017175754.1	Ig	155..243	CDD:386229	21/90 (23%)
		7tm_GPCRs	<199..>308	CDD:391938	8/38 (21%)
		TM helix 4	245..265	CDD:341315
		Ig_MOG_like	43..142	CDD:319291	25/99 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000