DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Cd276

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_877976.1	Gene:	Cd276 / 315716	RGDID:	727815	Length:	316	Species:	Rattus norvegicus

Alignment Length:	301	Identity:	65/301 - (21%)
Similarity:	105/301 - (34%)	Gaps:	86/301 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 GSGLVGLGTGTGTGSGCGPAIRWQLLLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQG 112
            |...||:..||..|           :|.|.|...:::.||.          |.|:.|.:.
  Rat     6 GGPSVGVSMGTALG-----------VLCLCLTGAVEVQVSE----------DPVVALVDT----- 44

  Fly   113 RDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAKAILAIHEHVIT-NNDR------------- 163
             |||..|..:...|.      |.....:.|...|.|.::    |..| ..|:
  Rat    45 -DATLRCSFSPEPGF------SLRQLNLIWQLTDTKQLV----HSFTEGRDQGSAYANRTALFPD 98

  Fly   164 LSVQHNDYNTWTLNIRGVKMEDAGKYMCQVNTDPMKMQTATLEVVIP---PDIINEETS----GD 221
            |.||.|.    :|.::.|::.|.|.|.|.|:.........:|:|..|   |.:..|...    ||
  Rat    99 LLVQGNA----SLRLQRVRVTDEGSYTCFVSIQDFDSAAVSLQVAAPYSKPSMTLEPNKDLRPGD 159

  Fly   222 MMVPEGGSAKLVCRA-RGHPKPKITWRREDGREIIARNGSHQKTKAQSVEGEMLTLSKITRSEMG 285
            |:.       :.|.: :|:|:.::.|:...|..:.    .:..|...:.|..:..:..:.|..:|
  Rat   160 MVT-------ITCSSYQGYPEAEVFWKDGQGLPLT----GNVTTSQMANERGLFDVHSVLRVVLG 213

  Fly   286 A---YMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAP 323
            |   |.|:..|.|         ||...|..|.:..|.:..|
  Rat   214 ANGTYSCLVRNPV---------LQQDAHGSVTITGQPMTFP 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	28/124 (23%)
		ig	102..195	CDD:278476	24/106 (23%)
		IG_like	219..307	CDD:214653	18/95 (19%)
		Ig	221..307	CDD:299845	17/89 (19%)
		Ig	311..404	CDD:299845	3/13 (23%)
		IG_like	327..405	CDD:214653
Cd276	NP_877976.1	IG_like	37..138	CDD:214653	26/120 (22%)
		Ig	44..139	CDD:299845	24/114 (21%)
		ig	151..231	CDD:278476	19/99 (19%)
		IG_like	156..238	CDD:214653	21/101 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	281..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910