DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-beta and Dscaml1

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_001101611.1 Gene:Dscaml1 / 315615 RGDID:1304887 Length:2111 Species:Rattus norvegicus


Alignment Length:526 Identity:115/526 - (21%)
Similarity:202/526 - (38%) Gaps:120/526 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 LTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGHRVSGDGSSAPAKVAWIKADAK 148
            |::|..: .|....|..:.|.|....:.|:.....|||:       |||   .|.::.|.| |.:
  Rat   641 LSISQSV-HVAVKVPPLIQPFEFPPASIGQLLYIPCVVS-------SGD---MPIRITWRK-DGQ 693

  Fly   149 AILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMC-QVNTDPMKMQTATLEVVIPPD 212
                    ||.:...::::..::.: :|.|..|.::..|.|.| ..|......:...|.|.:||.
  Rat   694 --------VIISGSGVTIESKEFMS-SLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPR 749

  Fly   213 IINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREIIARNGSHQK-------TKAQSVE 270
            .:.:..:.|.:.  |.:..|.|...|:|.||:.|:...|      :|:.|:       .:.|.:.
  Rat   750 FVVQPNNQDGIY--GKAGVLNCSVDGYPPPKVMWKHAKG------SGNPQQYHPVPLTGRIQILP 806

  Fly   271 GEMLTLSKITRSEMGAYMCIASNGVPPTVSKRMKLQVHFHPLVQVPNQLVGAPVLTDV------T 329
            ...|.:..:...::|.|:|.|||||...:||.|.|      .|::|..:...|..|..      .
  Rat   807 NSSLLIRHVLEEDIGYYLCQASNGVGTDISKAMFL------TVKIPAMITSHPNTTIAIKGHAKE 865

  Fly   330 LICNVEASPKAINYWQRENGEMIIAGD---RYALTEKENNMYAIEMILHIKRLQSSDFGG---YK 388
            |.|........|..|  |.|:.:|..|   |||:..|:|.    :.::...:|:.:|.|.   :.
  Rat   866 LNCTARGERPIIIRW--EKGDTVIDPDRVMRYAIATKDNG----DEVVSTLKLKPADRGDSVFFS 924

  Fly   389 CISKNSIGDTEGTIRLYEMERPGKKILRDDDLNEVSKNEVVQKDTRSEDG--------------- 438
            |.:.||.|:..|.|:|...|.|....|   ::.||....:..:.|:..||               
  Rat   925 CHAINSYGEDRGLIQLTVQEPPDPPEL---EIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKS 986

  Fly   439 --------SRNLNGRLYKDRAPDQHPAS------GSDQLLGRGTMRLIGTFLLALLVLFTALAEA 489
                    :||::..:.:....|.||||      .|...:||....      ..|.:.....|..
  Rat   987 DSWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPS------KELTISTEEAAPD 1045

  Fly   490 GP---TTLSCRTKGGRQKKAKETSWNG--RRARDGREDGHAAEWRQCWERSALSWRRSAPPELDY 549
            ||   .||...|     .::.:.:|..  :..::|...|:           .:.:|.::|.....
  Rat  1046 GPPMDVTLQPVT-----SQSIQVTWKAPKKELQNGIIRGY-----------QIGYRENSPGSNGQ 1094

  Fly   550 YSLIQL 555
            ||::::
  Rat  1095 YSIVEM 1100

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352 25/111 (23%)
ig 102..195 CDD:278476 21/93 (23%)
IG_like 219..307 CDD:214653 26/94 (28%)
Ig 221..307 CDD:299845 26/92 (28%)
Ig 311..404 CDD:299845 26/104 (25%)
IG_like 327..405 CDD:214653 22/89 (25%)
Dscaml1NP_001101611.1 IG 101..173 CDD:214652
IGc2 101..168 CDD:197706
Ig 183..276 CDD:299845
IG_like 195..276 CDD:214653
I-set 291..369 CDD:254352
IGc2 298..359 CDD:197706
IGc2 386..447 CDD:197706
I-set 466..560 CDD:254352
Ig 466..556 CDD:299845
IGc2 577..635 CDD:197706
IG_like 665..744 CDD:214653 21/98 (21%)
Ig 673..739 CDD:143165 19/85 (22%)
I-set 748..843 CDD:254352 27/108 (25%)
Ig7_DSCAM 765..843 CDD:143211 24/89 (27%)
I-set 849..942 CDD:254352 25/98 (26%)
Ig 861..949 CDD:299845 25/93 (27%)
FN3 945..1039 CDD:238020 18/102 (18%)
FN3 1046..1143 CDD:238020 12/71 (17%)
fn3 1151..1237 CDD:278470
FN3 1249..1340 CDD:238020
IGc2 1364..1428 CDD:197706
FN3 1442..1532 CDD:238020
FN3 1546..1618 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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