DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-beta and rst

DIOPT Version :9

Sequence 1:NP_001138225.1 Gene:DIP-beta / 33125 FlyBaseID:FBgn0259245 Length:555 Species:Drosophila melanogaster
Sequence 2:NP_001284835.1 Gene:rst / 31290 FlyBaseID:FBgn0003285 Length:764 Species:Drosophila melanogaster


Alignment Length:538 Identity:117/538 - (21%)
Similarity:193/538 - (35%) Gaps:156/538 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 LLLLGNCIDLTVSNKISSVG----AFEPDFVIPLENVTIAQGRDATFTC-VVNNLGGHRVSGDGS 134
            ||||...:.:..|:..:|..    |.||      ::.|...|...|..| |:|..|         
  Fly     7 LLLLATIVGMVRSSPYTSYQNQRFAMEP------QDQTAVVGARVTLPCRVINKQG--------- 56

  Fly   135 SAPAKVAWIKAD-----AKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKYMCQVN 194
                .:.|.|.|     ::.:.....:.:..:|    :..||   :|:|..|.::|..:|.|||:
  Fly    57 ----TLQWTKDDFGLGTSRDLSGFERYAMVGSD----EEGDY---SLDIYPVMLDDDARYQCQVS 110

  Fly   195 TDP-----MKMQTATLEVVIPPDIINEETSGDMM-VPEGGSAKLVC-RARGHPKPKITWRREDG- 251
            ..|     ::...|.|.|::||: ..:.|.||:: ..|....::.| ...|.|..:|||  .|| 
  Fly   111 PGPEGQPAIRSTFAGLTVLVPPE-APKITQGDVIYATEDRKVEIECVSVGGKPAAEITW--IDGL 172

  Fly   252 REIIARN--------GSHQKTKAQSVEGEMLTLSKITRSEMGAYMCIASNGVPPTV-SKRMKLQV 307
            ..::..|        ...::..|:||    |.|:.........:.|.|.|....|. |.:::::|
  Fly   173 GNVLTDNIEYTVIPLPDQRRFTAKSV----LRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEV 233

  Fly   308 HFHPLVQV---------------------PNQLVGAPVL--TDVTLICNVEASPKAINYWQRENG 349
            .:.|.|:|                     .:...|:.::  :.|.|.|..:|:|..:.|....|.
  Fly   234 KYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFIND 298

  Fly   350 EMIIAGDRYALTEKENNMYAIEMILHIKRLQSSDFGGYKCISKNSIGDTEGTIRL---YE---ME 408
            |.||.|.:            .||::.....:..| ...||..:||:|.:|.:..|   |.   .:
  Fly   299 EPIIGGQK------------TEMVIRNVTRKFHD-AIVKCEVQNSVGKSEDSETLDISYAPSFRQ 350

  Fly   409 RP-------GKKILRDDDLNEVSKNEVV---QKDTRSEDGSRNLN--------GRLY-KDRAP-- 452
            ||       |..:....:::...:.|:|   ....|....|.||.        ||.| |...|  
  Fly   351 RPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTFSVSNETAGRYYCKANVPGY 415

  Fly   453 -----DQH------PASGSDQLLGRGTMRLIGTFLLALLVLFTALAEAGPTTLSCRTKGGRQKKA 506
                 |.:      ||.||.    |....|:|.         ||..|...:::         .:|
  Fly   416 AEISADAYVYLKGSPAIGSQ----RTQYGLVGD---------TARIECFASSV---------PRA 458

  Fly   507 KETSWNGRRARDGREDGH 524
            :..||.........|.||
  Fly   459 RHVSWTFNGQEISSESGH 476

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-betaNP_001138225.1 I-set 98..209 CDD:254352 26/121 (21%)
ig 102..195 CDD:278476 21/98 (21%)
IG_like 219..307 CDD:214653 22/99 (22%)
Ig 221..307 CDD:299845 21/97 (22%)
Ig 311..404 CDD:299845 24/115 (21%)
IG_like 327..405 CDD:214653 21/80 (26%)
rstNP_001284835.1 IG_like 34..130 CDD:214653 26/121 (21%)
Ig 42..114 CDD:299845 20/91 (22%)
C2-set_2 135..225 CDD:285423 22/95 (23%)
Ig_3 265..329 CDD:290638 17/76 (22%)
I-set 346..420 CDD:254352 14/73 (19%)
Ig 360..425 CDD:299845 13/64 (20%)
Ig5_KIRREL3-like 428..524 CDD:143235 16/71 (23%)
IG_like 435..524 CDD:214653 12/64 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.