DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Pdcd1lg2

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	NP_001101052.2	Gene:	Pdcd1lg2 / 309304	RGDID:	1306403	Length:	268	Species:	Rattus norvegicus

Alignment Length:	205	Identity:	46/205 - (22%)
Similarity:	83/205 - (40%)	Gaps:	48/205 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 LLLLLLLGNCIDLTVSNKISSVGAFEPDFVI--PLENVTIAQGRDATFTC-----VVNNLGG--- 126
            :|||||:     |.:|:::..:.|.   |.:  |.|..|:..|...:..|     ....|.|
  Rat     1 MLLLLLI-----LNLSSQLHHIAAL---FTVTAPKEVYTVDFGSSVSLECDFDRRECTELEGIRA 57

  Fly   127 --HRVSGDGSSAPAKVAWIKADAKAILAIHEHVITNNDRLSVQHNDYNTWTLNIRGVKMEDAGKY 189
              .:|..|.||...:...:    :.:|.:.:.                  :.:|..|::.|:|:|
  Rat    58 SLQKVENDTSSQSQRATLL----EELLPLGKA------------------SFHIPSVQVRDSGQY 100

  Fly   190 MCQVNTDPMKMQTATLEVVIPPDIINEETSGDMMVPEGGSAKLVCRARGHPKPKITWRREDGREI 254
            .|.|... .......|.|.:....:..:| |.:.||..|..:|:|:|||:|..:::|:...
  Rat   101 RCLVICG-AAWDYKYLTVKVKASYVRIDT-GILEVPGTGEVQLICQARGYPLAEVSWQNVS---- 159

  Fly   255 IARNGSHQKT 264
            :..|.||.:|
  Rat   160 VPANTSHIRT 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	22/122 (18%)
		ig	102..195	CDD:278476	19/104 (18%)
		IG_like	219..307	CDD:214653	15/46 (33%)
		Ig	221..307	CDD:299845	14/44 (32%)
		Ig	311..404	CDD:299845
		IG_like	327..405	CDD:214653
Pdcd1lg2	NP_001101052.2	IG_like	28..119	CDD:214653	20/113 (18%)
Pdcd1lg2	NP_001101052.2	Ig	137..193	CDD:299845	12/37 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000