DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-beta and Btn2a2

DIOPT Version :9

Sequence 1:	NP_001138225.1	Gene:	DIP-beta / 33125	FlyBaseID:	FBgn0259245	Length:	555	Species:	Drosophila melanogaster
Sequence 2:	XP_038952161.1	Gene:	Btn2a2 / 306957	RGDID:	1306973	Length:	555	Species:	Rattus norvegicus

Alignment Length:	187	Identity:	40/187 - (21%)
Similarity:	72/187 - (38%)	Gaps:	33/187 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LLLLLLGNCIDLTVSNKISSVGAFEPDFVIPLENVTIAQGRDATFTCVVNNLGGH-RVSGDGSSA 136
            ||..|:.:.:.| :|.:.:.:|..||...:..||:|:                 | .::.:.::.
  Rat    15 LLFFLVLSLLAL-LSAQFTVIGPAEPILAMVGENITL-----------------HCHLTPERNAE 61

  Fly   137 PAKVAWIK-ADAKAILAIHEH-------VITNNDRLSVQHNDYNTW--TLNIRGVKMEDAGKYMC 191
            ..:|.|.: ..:.|:|....|       ::....|.:....|.:..  .|.|..|...|.|.|.|
  Rat    62 DMEVRWFRWRFSPAVLVYRGHQERPEEQMVPYQGRTTFMSTDISKGRVALIIHNVTTYDNGIYYC 126

  Fly   192 QVNTDPMKMQTATLEVVIPPDIINEETSGDMMVPEGGSAKLVCRARG-HPKPKITWR 247
            ... :......||:.:.:..  :..|....|...|.||..|.|.:.| :|:|:..||
  Rat   127 YFQ-EGRSYDQATIRLRVAS--LGSEPLIQMKTLEDGSILLKCTSGGWYPEPRAVWR 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-beta	NP_001138225.1	I-set	98..209	CDD:254352	21/121 (17%)
		ig	102..195	CDD:278476	18/103 (17%)
		IG_like	219..307	CDD:214653	11/30 (37%)
		Ig	221..307	CDD:299845	11/28 (39%)
		Ig	311..404	CDD:299845
		IG_like	327..405	CDD:214653
Btn2a2	XP_038952161.1	IgV_MOG_like	31..144	CDD:409378	23/130 (18%)
		Ig strand B	48..52	CDD:409378	1/20 (5%)
		Ig strand C	64..68	CDD:409378	1/3 (33%)
		Ig strand E	109..113	CDD:409378	1/3 (33%)
		Ig strand F	123..128	CDD:409378	2/4 (50%)
		Ig strand G	136..139	CDD:409378	1/2 (50%)
		SPRY_PRY_BTN1_2	344..514	CDD:293991
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000